Target Site Alterations & Resistance

Target site alteration is one of the mechanisms though which resistance to drugs can occur. For instance, amino acid substitutions can lead to an altered binding site for the drug which can lead to a decrease in the binding affinity of the drug to the target, thus conferring resistance to the drug. Here is the latest research on target site alterations and resistance.

May 20, 2020
Open Access

Why orthoptera fauna resist of pesticide? First experimental data of resistance phenomena

Data in Brief
Djamel BrahimiMohammed Belbachir
May 10, 2020

Biocontrol of mosquito vectors through herbal-derived silver nanoparticles: prospects and challenges

Environmental Science and Pollution Research International
Dinesh KumarVeena Agrawal
July 3, 2020
Open Access

Current status of in vivo bioanalysis of nano drug delivery systems

Journal of Pharmaceutical Analysis
Tingting WangJingkai Gu
May 6, 2020
Open Access

Breaking through the glioblastoma micro-environment via extracellular vesicles

Thomas SimonGeorgios Giamas
May 14, 2020
Open Access

Insecticide resistance in Anopheles stephensi in Somali Region, eastern Ethiopia

Malaria Journal
Solomon YaredTamar E Carter
April 15, 2020

Enhanced metabolism and selection of pyrethroid-resistant western corn rootworms (Diabrotica virgifera virgifera LeConte)

Pesticide Biochemistry and Physiology
Dariane SouzaBlair D Siegfried
July 2, 2020

Molecular mechanisms associated with quinolone resistance in Enterobacteriaceae: review and update

Transactions of the Royal Society of Tropical Medicine and Hygiene
Robab AzargunShirin Eyvazi
May 11, 2020

Targeting Antimicrobial Drug Resistance with Marine Natural Products

International Journal of Antimicrobial Agents
Filipa BarbosaEmília Sousa
April 24, 2020

An Insight into the Current Perspective and Potential Drug Targets for Visceral Leishmania (VL)

Current Drug Targets
Rani Mansuri, Jagbir Singh
July 31, 2020
Open Access

Insecticide resistance status of Aedes aegypti in Bangladesh

BioRxiv : the Preprint Server for Biology
H. M. Al-AminAudrey Lenhar
May 4, 2020

Investigation of resistance mechanism to fomesafen in Amaranthus retroflexus L

Pesticide Biochemistry and Physiology
Zhaofeng HuangShouhui Wei
July 21, 2020

An Overview of the Treatment of Less Common Non-Lactose Fermenting Gram Negative Bacteria

Hannah K SpencerSamuel L Aitken

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