Targeted Gene Correction

Targeted gene repair is a technique that can be used to change the DNA sequence at a specific site in the genome to either correct or introduce a genetic mutation. Here is the latest research on targeted gene correction.

December 31, 2020
Open Access

Knockdown of lactate dehydrogenase by adeno-associated virus-delivered CRISPR/Cas9 system alleviates primary hyperoxaluria type 1

Clinical and Translational Medicine
Rui ZhengHongquan Geng
November 29, 2020
Open Access

An inducible CRISPR interference library for genetic interrogation of Saccharomyces cerevisiae biology

Communications Biology
Amir Momen-RoknabadiSaeed Tavazoie
January 18, 2021
Review

Signaling pathways involved in cell cycle arrest during the DNA breaks

DNA Repair
Fatemeh SadoughiBahman Yousefi
January 15, 2021
Preprint
Open Access

Optimizing COVID-19 control with asymptomatic surveillance testing in a university environment

MedRxiv : the Preprint Server for Health Sciences
Cara E BrookMike Boots
December 18, 2020
Preprint
Open Access

IGI-LuNER: single-well multiplexed RT-qPCR test for SARS-CoV-2

MedRxiv : the Preprint Server for Health Sciences
Elizabeth C StahlJennifer A Doudna
November 22, 2020
Open Access

An oligomeric switch controls the Mrr-induced SOS response in E. coli

DNA Repair
Anaïs C BourgesNathalie Declerck
December 17, 2020

CRISPRing future medicines

Expert Opinion on Drug Discovery
Laure Grand MourselAnne-Marie Zuurmond
January 16, 2021
Open Access

Gene Therapy for Drug-Resistant Glioblastoma via Lipid-Polymer Hybrid Nanoparticles Combined with Focused Ultrasound

International Journal of Nanomedicine
Qiang YangYuan Cheng
November 25, 2020

Advances in gene therapy for β-thalassemia and hemophilia based on the CRISPR/Cas9 technology

Yi chuan = Hereditas
Li Wen BaoFan Yi Zeng
December 8, 2020
Open Access

CRISPR-Cas13a Targeting the Enhancer RNA-SMAD7e Inhibits Bladder Cancer Development Both in vitro and in vivo

Frontiers in Molecular Biosciences
Wenan CheYuandong Sun
January 2, 2021
Review

CRISPR-cas9 genome editing delivery systems for targeted cancer therapy

Life Sciences
Asma GhaemiMona Alibolandi
January 5, 2021
Open Access

Human Molecular Genetics and Genomics - Important Advances and Exciting Possibilities

The New England Journal of Medicine
Francis S CollinsCharles N Rotimi
November 25, 2020
Open Access

The Ig heavy chain protein but not its message controls early B cell development

Proceedings of the National Academy of Sciences of the United States of America
Muhammad Assad AslamHeinz Jacobs
December 31, 2020
Open Access

USP15 Deubiquitinase Safeguards Hematopoiesis and Genome Integrity in Hematopoietic Stem Cells and Leukemia Cells

Cell Reports
Paul van den BerkElisabetta Citterio

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