Targeting ALK: Precision Medicine

Anaplastic Lymphoma Kinase (ALK) is an oncogene frequently found as a fusions in non-small cell lung cancer (NSCLC), as EML4-ALK. Precision medicine uses therapeutic agents that target specific mutations, such as those found in ALK-positive NSCLC patients. Discover the latest research on Targeting ALK here.

June 19, 2020
Case Report
Open Access

Breast Implant-Associated Anaplastic Large Cell Lymphoma

Case Reports in Pathology
P L MooriJ Iddon
June 17, 2020

Novel PNPT1-ALK fusion variant exerted significant benefit to crizotinib in NSCLC

Lung Cancer : Journal of the International Association for the Study of Lung Cancer
Linling JinXin Zhao
June 17, 2020

The clinical efficacy of combinatorial therapy of EGFR-TKI and crizotinib in overcoming MET amplification-mediated resistance from prior EGFR-TKI therapy

Lung Cancer : Journal of the International Association for the Study of Lung Cancer
Yubo WangYong He
June 17, 2020

Identification of target small molecule tyrosine kinase inhibitors that need monitoring and clinical application of protocol for early detection of cancer therapeutics-related cardiac dysfunction using signal detection: An investigation of real world data

Journal of Oncology Pharmacy Practice : Official Publication of the International Society of Oncology Pharmacy Practitioners
Takahito MizunoFumiko Ohtsu
June 25, 2020
Case Report

A case of ROS1-rearranged lung adenocarcinoma with osteoblastic bone metastasis

Respiratory Medicine Case Reports
Yutaka TakaharaShiro Mizuno
June 11, 2020

BRAF V600E mutation and MET amplification as resistance pathways of the second-generation anaplastic lymphoma kinase (ALK) inhibitor alectinib in lung cancer

Lung Cancer : Journal of the International Association for the Study of Lung Cancer
Ruoshi ShiGeoffrey Liu
June 22, 2020

Investigation on the prognostic impact of concurrent genomic alterations in crizotinib-treated EML4-ALK-rearranged advanced non-small cell lung cancer patients

Lung Cancer : Journal of the International Association for the Study of Lung Cancer
Jing ZhengJianying Zhou
July 1, 2020
Comment / Editorial

Have We Revealed the Achilles' Heel of Brigatinib? Implications on Clinical Practice

Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer
Herbert H LoongYat-Ming Lau
June 25, 2020
Review
Open Access

The Role of MET Inhibitor Therapies in the Treatment of Advanced Non-Small Cell Lung Cancer

Journal of Clinical Medicine
Ramon Andrade De MelloGeorgios Antoniou
July 3, 2020
Case Report

A case of ALK- rearranged lung adenocarcinoma associated with syndrome of inappropriate antidiuretic hormone

Respiratory Medicine Case Reports
Yoshihiro MiyashitaToshio Oyama
June 25, 2020
Case Report

Nivolumab-induced contact dermatitis in a patient with advanced lung cancer

Respiratory Medicine Case Reports
Shintaro SatoHidekazu Matsushima
June 25, 2020
Case Report

Chr2 30297612-ALK, A Novel Intergenic Fusion With Exon18 of ALK, Responds to Crizotinib

Clinical Lung Cancer
Xiaofeng ChenDerong Zhang

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