Feed Preview

Tau Aggregation: Genomics

Tau Aggregation: Genomics diagram by Designua, Shutterstock
Designua, Shutterstock

Tau Aggregation is an important characteristic in some neurodegenerative disorders, including Alzheimer’s Disease. Discover the latest research using genomics to understand Tau Aggregation.

Top 20 most recent papers
The Journal of Physical Chemistry. B

Tau R3-R4 Domain Dimer of the Wild Type and Phosphorylated Ser356 Sequences. I. In Solution by Atomistic Simulations

The Journal of Physical Chemistry. BMarch 29, 2020
Philippe DerreumauxPhuong Hoang Nguyen
Nature Reviews. Neurology

Protein transmission in neurodegenerative disease

Nature Reviews. NeurologyMarch 24, 2020
Chao PengVirginia M-Y Lee
68
1
Frontiers in Endocrinology

Behavioral Abnormalities in Knockout and Humanized Tau Mice

Frontiers in EndocrinologyApril 1, 2020
Rafaella Araujo GonçalvesFernanda G De Felice
Acta Neuropathologica Communications

Neuropathological correlates of parkinsonian disorders in a large Dutch autopsy series

Acta Neuropathologica CommunicationsMarch 29, 2020
H GeutW D J van de Berg
5
1
Nature Reviews. Neurology

Development of disease-modifying drugs for frontotemporal dementia spectrum disorders

Nature Reviews. NeurologyMarch 24, 2020
Francesco PanzaBruno P Imbimbo
25
Biochemical and Biophysical Research Communications

Growth arrest specific protein 7 inhibits tau fibrillogenesis

Biochemical and Biophysical Research CommunicationsMarch 29, 2020
Taiki ShimizuTakafumi Uchida
bioRxiv

FRET-based Tau seeding assay does not represent prion-like templated assembly of Tau fibers

bioRxivMarch 25, 2020
Senthilvelrajan KaniyappanEckhard Mandelkow
17
Journal of Neuroinflammation

Role of dietary fatty acids in microglial polarization in Alzheimer's disease

Journal of NeuroinflammationMarch 27, 2020
Smita Eknath Desale, Subashchandrabose Chinnathambi
ACS Sensors

Mechanisms of heparin-induced tau aggregation revealed by single nanopore

ACS SensorsMarch 29, 2020
Nicoletta GiamblancoSebastien Balme
7
Journal of Molecular Recognition : JMR

Understanding the disrupting mechanism of the Tau aggregation motif "306 VQIVYK311 " by phenylthiazolyl-hydrazides inhibitors

Journal of Molecular Recognition : JMRApril 1, 2020
Elena Moreno-CastilloPedro A Valiente
Journal of Personalized Medicine

Flotillin: A Promising Biomarker for Alzheimer's Disease

Journal of Personalized MedicineApril 1, 2020
Efthalia AngelopoulouChristina Piperi

See more papers from this feed

Related Feeds

ALS

Amyotrophic Lateral Sclerosis (ALS), also known as motor neuron disease, is associated with the death of neurons that control voluntary muscles. Discover the latest research on ALS here.

ALS & FTD: TDP-43

ALS shares with a considerable proportion of FTD cases the same neuropathological substrate, namely, inclusions of abnormally phosphorylated protein tdp-43 (ptdp-43). Here are the latest discoveries pertaining to ptdp-43 and these diseases.

ALS - Pathogenic Mechanisms

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by muscle weakness. Here is the latest research investigating pathogenic mechanisms that underlie this genetically heterogeneous disorder.

ALS - Phenotypes

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by muscle weakness. Here is the latest research investigating phenotypes associated with this genetically heterogeneous disorder.

ALS: Genetics

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by muscle weakness. ALS is a genetically heterogeneous disorder with several causative genes. Here are the latest discoveries pertaining to the genetics of this disease.

ALS: Prions

Prions are misfolded proteins which characterize several fatal neurodegenerative diseases. Prion-like mechanisms are associated with the pathogenesis of Amyotrophic Lateral Sclerosis (ALS). Here are the latest discoveries pertaining to this disease.

ALS: Stress Granules

Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease characterized by cytoplasmic protein aggregates within motor neurons. TDP-43 is an ALS-linked protein that is known to regulate splicing and storage of specific mRNAs into stress granules, which have been implicated in formation of ALS protein aggregates. Here is the latest research.

ALS: Therapies

Amyotrophic Lateral Sclerosis (ALS), also known as motor neuron disease, is associated with the death of neurons that control voluntary muscles. Discover the latest research on ALS therapies here.

ALS: Transposon de-silencing

Transposon silencing is a form of transcriptional gene silencing. These gene silencing mechanisms are impaired in Amyotrophic lateral sclerosis (ALS). Here are the latest discoveries pertaining to transposon silencing and this disease.

Age-related Dementia

Age-related dementia (Alzheimer's disease) results from the destructive impact of the pulse on cerebral vasculature. Evidence is reviewed that the neuropathology of the dementia is caused by the breakdown of small cerebral vessels (silent microbleeds), that the microbleeds result from pulse-induced damage to the cerebral vessels, and that pulse becomes increasingly destructive with age, because of the age-related stiffening of the aorta and great arteries, which causes an increase in the intensity of the pressure pulse. Discover the latest research on age-related dementia here.

© 2020 Meta ULC. All rights reserved
/feed-previews/tau-aggregation-genomics/dd022db5-6b6e-48b7-a623-82e481dc12ef