Tau and Neurodegeneration

Tau proteins include six highly soluble protein isoforms produced by alternative splicing from the gene MAPT (microtubule-associated protein tau). Combating tau-associated pathologies is a key focus of neurodegeneration research. Here is the latest research on tau and neurodegeneration.

August 1, 2020

Modification of lipid rafts by extracellular vesicles carrying HIV-1 protein Nef induces redistribution of APP and Tau causing neuronal dysfunction

The Journal of Biological Chemistry
Michael DitiatkovskiDmitri Sviridov
July 30, 2020
Review
Open Access

Use of Biomarkers in Ongoing Research Protocols on Alzheimer's Disease

Journal of Personalized Medicine
Marco CanevelliNicola Vanacore
July 10, 2020
Review
Open Access

Understanding cause and effect in Alzheimer's pathophysiology: implications for clinical trials

Neuropathology and Applied Neurobiology
Delphine Boche, James A R Nicoll
July 19, 2020

Blood cell-produced amyloid-β induces cerebral Alzheimer-type pathologies and behavioral deficits

Molecular Psychiatry
Hao-Lun SunYan-Jiang Wang
July 23, 2020

The effect of lumbar puncture on the neurodegeneration biomarker neurofilament light in macaque monkeys

Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring
Susan E BoehnkeDouglas P Munoz
July 28, 2020
Review
Open Access

Tau and Alpha Synuclein Synergistic Effect in Neurodegenerative Diseases: When the Periphery Is the Core

International Journal of Molecular Sciences
Elena VacchiGiorgia Melli
July 6, 2020

One stop shop: Flortaucipir PET differentiates amyloid positive and negative forms of neurodegenerative diseases

Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
Jochen HammesThilo van Eimeren
July 24, 2020
Preprint
Open Access

Plasma amyloid, phosphorylated tau, and neurofilament light for individualized risk prediction in mild cognitive impairment

MedRxiv : the Preprint Server for Health Sciences
N. C. CullenOskar Hansson
July 21, 2020
Review

Mitochondria as a promising target for developing novel agents for treating Alzheimer's disease

Medicinal Research Reviews
Elena F ShevtsovaSergey O Bachurin
July 28, 2020
Review
Open Access

Endosomal-Lysosomal Processing of Neurodegeneration-Associated Proteins in Astrocytes

International Journal of Molecular Sciences
Ching-On Wong
July 18, 2020

Viral Delivery of Non-Mutated Human Truncated Tau to Neurons Recapitulates Key Features of Human Tauopathy in Wild-Type Mice

Journal of Alzheimer's Disease : JAD
Thomas VogelsTomáš Hromádka
July 17, 2020
Open Access

Longitudinal changes in EEG power, sleep cycles and behaviour in a tau model of neurodegeneration

Alzheimer's Research & Therapy
C M HoltonK A Wafford
July 17, 2020
Open Access

18F-MK-6240 PET for early and late detection of neurofibrillary tangles

Brain : a Journal of Neurology
Tharick A PascoalPedro Rosa-Neto
July 28, 2020
Review

Somatic mutations in neurodegeneration: An update

Neurobiology of Disease
Christos Proukakis
July 5, 2020
Preprint
Open Access

A model of traumatic brain injury using human iPSC-derived cortical brain organoids

BioRxiv : the Preprint Server for Biology
J. D. LaiJustin Ichida

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