Tau & Neurodegeneration

Tau proteins include six highly soluble protein isoforms produced by alternative splicing from the gene MAPT (microtubule-associated protein tau). Combating tau-associated pathologies is a key focus of neurodegeneration research. Here is the latest research on tau and neurodegeneration.

December 7, 2021

Differential expression of tau species and the association with cognitive decline and synaptic loss in Alzheimer's disease.

Alzheimer's & Dementia : the Journal of the Alzheimer's Association
Sivaprakasam R SarojaAna C Pereira
December 6, 2021
Open Access

Tracing the genetics of neurological disease to the mutation-directed addition of single hydrogen bonds

BioRxiv : the Preprint Server for Biology
x. zhouS. McKnight
December 6, 2021
Open Access

Microcontact Printing of Cholinergic Neurons in Organotypic Brain Slices.

Frontiers in Neurology
Katharina Steiner, Christian Humpel
December 6, 2021
Open Access

Recent High-Resolution Structures of Amyloids Involved in Neurodegenerative Diseases.

Frontiers in Aging Neuroscience
Rodrigo Diaz-Espinoza
December 6, 2021
Open Access

It Is Time to Study Overlapping Molecular and Circuit Pathophysiologies in Alzheimer's and Lewy Body Disease Spectra.

Frontiers in Systems Neuroscience
Noritaka Wakasugi, Takashi Hanakawa
December 6, 2021
Open Access

Exploration of Aberrant E3 Ligases Implicated in Alzheimer's Disease and Development of Chemical Tools to Modulate Their Function.

Frontiers in Cellular Neuroscience
Frances M Potjewyd, Alison D Axtman
December 6, 2021

Biomarkers of Cerebral Glucose Metabolism and Neurodegeneration in Parkinson's Disease: A Cerebrospinal Fluid-Based Study.

Journal of Parkinson's Disease
Claudio LiguoriMariangela Pierantozzi
December 6, 2021

Prions and Neurodegenerative Diseases: A Focus on Alzheimer's Disease.

Journal of Alzheimer's Disease : JAD
Alessio CrestiniVincenzo Mattei
December 4, 2021

Blood-based biomarkers for Alzheimer's disease.

EMBO Molecular Medicine
Antoine LeuzyOskar Hansson
December 4, 2021
Open Access

Human Induced Pluripotent Stem Cell Models of Frontotemporal Dementia With Tau Pathology.

Frontiers in Cell and Developmental Biology
Rebekka KühnGunnar Hargus
December 3, 2021

Microtubule-modulating agents in the fight against neurodegeneration: Will it ever work?

Current Neuropharmacology
Ahmed SolimanRoland Brandt
December 3, 2021

The Link between Exercise and Homocysteine in the Alzheimer's Disease: A Bioinformatic Network Model.

CNS & Neurological Disorders Drug Targets
Luana Lemos LeãoRenato Sobral Monteiro-Junior
December 3, 2021

The formation of small aggregates contributes to the neurotoxic effects of tau45-230.

Neurochemistry International
Sana Afreen, Adriana Ferreira
December 3, 2021

The metabolic signaling of the nucleoredoxin-like 2 gene supports brain function.

Redox Biology
Céline JaillardThierry Léveillard
December 1, 2021

Inflammasome activation in neurodegenerative diseases.

Essays in Biochemistry
Kishore Aravind Ravichandran, Michael T Heneka
December 1, 2021

Targeted proteolytic products of τ and α-synuclein in neurodegeneration.

Essays in Biochemistry
Yuxing XiaBenoit I Giasson
November 29, 2021

Acrolein, an endogenous aldehyde induces Alzheimer's disease-like pathologies in mice: A new sporadic AD animal model.

Pharmacological Research : the Official Journal of the Italian Pharmacological Society
Chen ChenRongbiao Pi

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