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Tauopathies

Tauopathies diagram by undefined

Tauopathies are neurodegenerative disorders caused due to misfolding and aggregation of the tau protein in neurofibrillary tangles in the brain. Discover the latest research on tauopathies here.

Top 20 most recent papers
Blood

ELEVATE TN: Phase 3 Study of Acalabrutinib Combined with Obinutuzumab (O) or Alone Vs O Plus Chlorambucil (Clb) in Patients (Pts) with Treatment-Naive Chronic Lymphocytic Leukemia (CLL)

BloodNovember 13, 2019
Jeff P SharmanJohn C. Byrd
Blood

Combined Ibrutinib and Venetoclax for First-Line Treatment for Patients with Chronic Lymphocytic Leukemia (CLL)

BloodNovember 13, 2019
Nitin K JainWilliam G Wierda
Blood

Ibrutinib (Ibr) Plus Venetoclax (Ven) for First-Line Treatment of Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL): Results from the MRD Cohort of the Phase 2 CAPTIVATE Study

BloodNovember 13, 2019
Constantine S TamWilliam G Wierda
Neurology

Cerebrospinal fluid dynamics disorders: Relationship to Alzheimer biomarkers and cognition

NeurologyNovember 12, 2019
Jonathan Graff-RadfordClifford R. Jack
4
Blood

Preliminary Safety and Efficacy Results from a Phase 2 Study of Acalabrutinib, Venetoclax and Obinutuzumab in Patients with Previously Untreated Chronic Lymphocytic Leukemia (CLL)

BloodNovember 13, 2019
Benjamin L LampsonMatthew S Davids
JAMA Neurology

Reactions to Multiple Ascending Doses of the Microtubule Stabilizer TPI-287 in Patients With Alzheimer Disease, Progressive Supranuclear Palsy, and Corticobasal Syndrome: A Randomized Clinical Trial

JAMA NeurologyNovember 11, 2019
Richard M TsaiAdam L. Boxer
14
1
Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine

Evaluation of dosimetry, quantitative methods and test-retest variability of 18 F-PI-2620 PET for the assessment of tau deposits in the human brain

Journal of Nuclear Medicine : Official Publication, Society of Nuclear MedicineNovember 11, 2019
Santiago BullichAndrew W Stephens
1
Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine

Tau PET imaging with 18 F-PI-2620 in patients with Alzheimer's disease and healthy controls: a first-in-human study

Journal of Nuclear Medicine : Official Publication, Society of Nuclear MedicineNovember 11, 2019
Andre MuellerAndrew W Stephens
1
Annals of Neurology

Midlife atherosclerosis and development of Alzheimer's or vascular dementia

Annals of NeurologyNovember 12, 2019
Anna-Märta GustavssonOskar Hansson
4
Brain and nerve = Shinkei kenkyū no shinpo

The Propagation Hypothesis of Prion-like Protein Agregates in Neurodegenerative Diseases

Brain and nerve = Shinkei kenkyū no shinpoNovember 1, 2019
Takashi Nonaka
EMBO Molecular Medicine

Cerebrospinal fluid and plasma biomarker trajectories with increasing amyloid deposition in Alzheimer's disease

EMBO Molecular MedicineNovember 11, 2019
Sebastian PalmqvistOskar Hansson
11
bioRxiv

A/T/N polygenic risk score for cognitive decline in old age

bioRxivNovember 12, 2019
Annah M. MooreTimothy J. Hohman
23
FEBS Letters

Tau (297-391) forms filaments that structurally mimic the core of paired helical filaments in Alzheimer's disease brain

FEBS LettersNovember 13, 2019
Youssra K Al-HilalyLouise C Serpell
Current Alzheimer Research

Tau PET distributional pattern in AD patients with visuospatial dysfunction

Current Alzheimer ResearchNovember 13, 2019
Xi SunGuihong Wang
Acta Neuropathologica Communications

N368-Tau fragments generated by legumain are detected only in trace amount in the insoluble Tau aggregates isolated from AD brain

Acta Neuropathologica CommunicationsNovember 13, 2019
Kerstin SchlegelLaura Gasparini
The Journal of General Virology

Eliminating transmissibility of bovine spongiform encephalopathy by dry-heat treatment

The Journal of General VirologyNovember 13, 2019
Yuichi MatsuuraShirou Mohri
Environmental Research

A possible relationship between telomere length and markers of neurodegeneration in rat brain after welding fume inhalation exposure

Environmental ResearchNovember 5, 2019
Mohammad ShoebJames M Antonini
3
Neurochemistry International

Melatonin attenuates streptozotocin-induced Alzheimer-like features in hyperglycemic rats

Neurochemistry InternationalNovember 11, 2019
Utcharaporn KamsrijaiPiyarat Govitrapong
Journal of Biophotonics

Step-by-step monitoring of a magnetic and SERS-active immunosensor assembly for purification and detection of tau protein

Journal of BiophotonicsNovember 13, 2019
Viktor MaurerRainer Stosch
Scientific Reports

Contribution of syndecans to cellular uptake and fibrillation of α-synuclein and tau

Scientific ReportsNovember 12, 2019
Anett HudákTamás Letoha

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