Feed Preview

Fast Growing

Tauopathies

Tauopathies diagram by Alila Medical Media, Shutterstock
Alila Medical Media, Shutterstock

Tauopathies are neurodegenerative disorders caused due to misfolding and aggregation of the tau protein in neurofibrillary tangles in the brain. Discover the latest research on tauopathies here.

Top 20 most recent papers
Journal of Alzheimer's Disease : JAD

Validation of Plasma Proteomic Biomarkers Relating to Brain Amyloid Burden in the EMIF-Alzheimer's Disease Multimodal Biomarker Discovery Cohort

Journal of Alzheimer's Disease : JADJanuary 28, 2020
Sarah WestwoodSimon Lovestone
JAMA Network Open

Association of Blood Biomarkers With Acute Sport-Related Concussion in Collegiate Athletes: Findings From the NCAA and Department of Defense CARE Consortium

JAMA Network OpenJanuary 25, 2020
Michael McCreaJon DiFiori
50
2
1
Cell Stem Cell

Interneuron Accumulation of Phosphorylated tau Impairs Adult Hippocampal Neurogenesis by Suppressing GABAergic Transmission

Cell Stem CellJanuary 25, 2020
Jie ZhengJian-Zhi Wang
23
1
Annals of Neurology

Imaging Biomarkers of Alzheimer's Disease in Multiple Sclerosis

Annals of NeurologyJanuary 24, 2020
Burcu ZeydanKejal Kantarci
10
bioRxiv

Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer's disease-like pathology in human cerebral organoids

bioRxivJanuary 27, 2020
Michela DeleidiCarlo Viscomi
The Journal of Cell Biology

The stress-responsive gene GDPGP1/mcp-1 regulates neuronal glycogen metabolism and survival

The Journal of Cell BiologyJanuary 23, 2020
Alexander SchulzMarc Hammarlund
10
Science Translational Medicine

The IDH-TAU-EGFR triad defines the neovascular landscape of diffuse gliomas

Science Translational MedicineJanuary 24, 2020
Ricardo GarginiPilar Sánchez-Gómez
Journal of the American Chemical Society

Enhanced In Vivo Blood-Brain-Barrier Penetration by Circular Tau-Transferrin Receptor Bifunctional Aptamer for Tauopathy Therapy

Journal of the American Chemical SocietyJanuary 29, 2020
Xiaowei LiWeihong Tan
Neurology

Better stress coping associated with lower tau in amyloid-positive cognitively unimpaired older adults

NeurologyJanuary 23, 2020
Eider M Arenaza-UrquijoPrashanthi Vemuri
1
The Journal of Biological Chemistry

A synthetic heparinoid blocks tau aggregate cell uptake and amplification

The Journal of Biological ChemistryJanuary 25, 2020
Barbara E StopschinskiMarc I Diamond
4
Proceedings of the National Academy of Sciences of the United States of America

Release of a disordered domain enhances HspB1 chaperone activity toward tau

Proceedings of the National Academy of Sciences of the United States of AmericaJanuary 25, 2020
Hannah E R BaughmanRachel E Klevit
bioRxiv

Herpes zoster in HIV-1 infection: the role of CSF pleocytosis in secondary CSF escape and discordance

bioRxivJanuary 28, 2020
Lars HagbergMagnus Gisslén
Aging Cell

"Amyloid-beta accumulation cycle" as a prevention and/or therapy target for Alzheimer's disease

Aging CellJanuary 26, 2020
Chinthalapally V RaoHiroshi Y Yamada
1
bioRxiv

GPCR-mediated clearance of tau in post-synaptic compartments attenuates tau pathology in vivo

bioRxivJanuary 23, 2020
Natura MyekuKaren E Duff
Neurobiology of Aging

Rho-kinase ROCK inhibitors reduce oligomeric tau protein

Neurobiology of AgingJanuary 27, 2020
Tadanori HamanoYasunari Nakamoto
5
The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine

Classifying Pubertal Development Using Child and Parent Report: Comparing the Pubertal Development Scales to Tanner Staging

The Journal of Adolescent Health : Official Publication of the Society for Adolescent MedicineJanuary 25, 2020
Maria Elisabeth Koopman-VerhoeffMary A Carskadon
Scientific Reports

A Small Compound Targeting Prohibitin with Potential Interest for Cognitive Deficit Rescue in Aging mice and Tau Pathology Treatment

Scientific ReportsJanuary 26, 2020
Anne-Cécile GuyotAloïse Mabondzo
4
Neurobiology of Disease

Neuronally expressed anti-tau scFv prevents tauopathy-induced phenotypes in Drosophila models

Neurobiology of DiseaseJanuary 27, 2020
S KrishnaswamyE M Sigurdsson
1
Acta Neuropathologica

ACE2 activation protects against cognitive decline and reduces amyloid pathology in the Tg2576 mouse model of Alzheimer's disease

Acta NeuropathologicaJanuary 27, 2020
Charles E EvansPatrick G Kehoe
6
bioRxiv

Effects of pharmacological modulators of α-synuclein and tau aggregation and internalization

bioRxivJanuary 28, 2020
Antonio Dominguez-MeijideTiago Fleming Outeiro

See more papers from this feed

Related Feeds

ALS

Amyotrophic Lateral Sclerosis (ALS), also known as motor neuron disease, is associated with the death of neurons that control voluntary muscles. Discover the latest research on ALS here.

ALS & FTD: TDP-43

ALS shares with a considerable proportion of FTD cases the same neuropathological substrate, namely, inclusions of abnormally phosphorylated protein tdp-43 (ptdp-43). Here are the latest discoveries pertaining to ptdp-43 and these diseases.

ALS - Pathogenic Mechanisms

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by muscle weakness. Here is the latest research investigating pathogenic mechanisms that underlie this genetically heterogeneous disorder.

ALS - Phenotypes

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by muscle weakness. Here is the latest research investigating phenotypes associated with this genetically heterogeneous disorder.

ALS: Genetics

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by muscle weakness. ALS is a genetically heterogeneous disorder with several causative genes. Here are the latest discoveries pertaining to the genetics of this disease.

ALS: Prions

Prions are misfolded proteins which characterize several fatal neurodegenerative diseases. Prion-like mechanisms are associated with the pathogenesis of Amyotrophic Lateral Sclerosis (ALS). Here are the latest discoveries pertaining to this disease.

ALS: Stress Granules

Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease characterized by cytoplasmic protein aggregates within motor neurons. TDP-43 is an ALS-linked protein that is known to regulate splicing and storage of specific mRNAs into stress granules, which have been implicated in formation of ALS protein aggregates. Here is the latest research.

ALS: Therapies

Amyotrophic Lateral Sclerosis (ALS), also known as motor neuron disease, is associated with the death of neurons that control voluntary muscles. Discover the latest research on ALS therapies here.

ALS: Transposon de-silencing

Transposon silencing is a form of transcriptional gene silencing. These gene silencing mechanisms are impaired in Amyotrophic lateral sclerosis (ALS). Here are the latest discoveries pertaining to transposon silencing and this disease.

Age-related Dementia

Age-related dementia (Alzheimer's disease) results from the destructive impact of the pulse on cerebral vasculature. Evidence is reviewed that the neuropathology of the dementia is caused by the breakdown of small cerebral vessels (silent microbleeds), that the microbleeds result from pulse-induced damage to the cerebral vessels, and that pulse becomes increasingly destructive with age, because of the age-related stiffening of the aorta and great arteries, which causes an increase in the intensity of the pressure pulse. Discover the latest research on age-related dementia here.

© 2020 Meta ULC. All rights reserved
/feed-previews/tauopathies/79cbac9b-3126-4814-a6b9-a83f020a462f