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Tauopathy Biochemistry

Tauopathy Biochemistry diagram by ibreakstock, Shutterstock
ibreakstock, Shutterstock

Tauopathies are neurodegenerative disorders that are caused due to the accumulation of abnormal tau proteins in neurons and/or the glia. Here is the latest research on tauopathy biochemistry.

Top 20 most recent papers
Chemical Reviews

Interrogating Amyloid Aggregates using Fluorescent Probes

Chemical ReviewsNovember 2, 2019
Amir AliyanAngel A Martí
6
1
21
bioRxiv

Novel tau filament fold in corticobasal degeneration, a four-repeat tauopathy

bioRxivOctober 21, 2019
Wenjuan ZhangSjors Scheres
66
9
JAMA Neurology

Diagnosis Across the Spectrum of Progressive Supranuclear Palsy and Corticobasal Syndrome

JAMA NeurologyDecember 21, 2019
Edwin JabbariHuw R Morris
132
1
bioRxiv

Site-specific hyperphosphorylation of tau inhibits its fibrillization in vitro, blocks its seeding capacity in cells, and disrupts its microtubule binding; Implications for the native state stabilization of tau

bioRxivSeptember 18, 2019
Hilal A LashuelMarc I Diamond
14
bioRxiv

Virtual screening of MAP-Tau protein inhibitors from Semecarpus anacardium Linn. leaf extract for cancer prevention

bioRxivJanuary 9, 2020
Rajesh Kumar SinghSantosh Kumar Singh
4
bioRxiv

CofActor: A light and redox-gated optogenetic clustering tool to study abnormal cytoskeletal dynamics in stressed cells

bioRxivNovember 28, 2019
Fatema B SalemRobert M Hughes
6
Scientific Reports

Computational redesign of the Escherichia coli ribose-binding protein ligand binding pocket for 1,3-cyclohexanediol and cyclohexanol

Scientific ReportsNovember 16, 2019
Diogo TavaresJan Roelof van der Meer
1
1
bioRxiv

Staufen 1 amplifies pro-apoptotic activation of the unfolded protein response.

bioRxivOctober 28, 2019
Mandi GandelmanStefan M Pulst
9
bioRxiv

Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson's disease at Chr16q11.2 and on the MAPT H1 allele.

bioRxivJanuary 7, 2020
Marc SoutarHelene Plun-Favreau
26
bioRxiv

25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner

bioRxivJanuary 15, 2020
Man Ying WongWenjie Luo
3
Angewandte Chemie

Site-specific hyperphosphorylation inhibits, rather than promotes, tau fibrillization, seeding capacity and its microtubule binding

Angewandte ChemieDecember 22, 2019
Mahmood Haj-YahyaHilal A Lashuel
7
1
Inorganic Chemistry

Binding and Reactivity of Copper to R1 and R3 Fragments of tau Protein

Inorganic ChemistryDecember 11, 2019
Chiara BacchellaSimone Dell'Acqua
11
1
Journal of Inorganic Biochemistry

Exploring the interactions of iron and zinc with the microtubule binding repeats R1 and R4

Journal of Inorganic BiochemistryJanuary 14, 2020
Soha AhmadiHeinz-Bernhard Kraatz
ACS Chemical Neuroscience

Probing The Non-Generalized Amyloid Inhibitory Mechanism Of Hydrophobic Chaperone

ACS Chemical NeuroscienceJanuary 15, 2020
Aiman MasroorRizwan Hasan Khan
Environmental Science and Pollution Research International

Metabolic impairments, metal traffic, and dyshomeostasis caused by the antagonistic interaction of cadmium and selenium using organic and inorganic mass spectrometry

Environmental Science and Pollution Research InternationalNovember 24, 2019
Gema Rodríguez-MoroTamara García-Barrera
4
Pakistan Journal of Pharmaceutical Sciences

Impacts of intake of bakery food chemicals, degraded water and psychiatric drugs on liver & renal functions of brain tumor patients

Pakistan Journal of Pharmaceutical SciencesNovember 5, 2019
Sana KhalidSajid Rasheed
American Journal of Translational Research

Hypoxia induces HT-22 neuronal cell death via Orai1/CDK5 pathway-mediated Tau hyperphosphorylation

American Journal of Translational ResearchJanuary 15, 2020
Binbin FangMengmeng Ou
1
Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring

Sets of coregulated serum lipids are associated with Alzheimer's disease pathophysiology

Alzheimer's & Dementia : Diagnosis, Assessment & Disease MonitoringSeptember 14, 2019
Dinesh Kumar BarupalAlzheimer Disease Metabolomics Consortium
9
1
23
International Journal of Biological Macromolecules

Effect of Disease-Linked Mutations on the Structure, Function, Stability and Aggregation of Human Carbonic Anhydrase II

International Journal of Biological MacromoleculesNovember 29, 2019
Preeti GuptaShashank Deep
ELife

Mitochondria supply ATP to the ER through a mechanism antagonized by cytosolic Ca2

ELifeSeptember 10, 2019
Jing YongRandal J Kaufman
125
41

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