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Tauopathy Biochemistry

Tauopathy Biochemistry diagram by undefined

Tauopathies are neurodegenerative disorders that are caused due to the accumulation of abnormal tau proteins in neurons and/or the glia. Here is the latest research on tauopathy biochemistry.

Top 20 most recent papers
Chemical Reviews

Interrogating Amyloid Aggregates using Fluorescent Probes

Chemical ReviewsNovember 1, 2019
Amir AliyanAngel A Martí
6
1
bioRxiv

Site-specific hyperphosphorylation of tau inhibits its fibrillization in vitro, blocks its seeding capacity in cells, and disrupts its microtubule binding; Implications for the native state stabilization of tau

bioRxivSeptember 18, 2019
Hilal Ahmed LashuelMarc I. Diamond
14
bioRxiv

Novel tau filament fold in corticobasal degeneration, a four-repeat tauopathy

bioRxivOctober 21, 2019
Wen-Juan ZhangSjors H. W. Scheres
66
Scientific Reports

Computational redesign of the Escherichia coli ribose-binding protein ligand binding pocket for 1,3-cyclohexanediol and cyclohexanol

Scientific ReportsNovember 15, 2019
Diogo TavaresJan Roelof van der Meer
bioRxiv

Staufen 1 amplifies pro-apoptotic activation of the unfolded protein response.

bioRxivOctober 28, 2019
Mandi GandelmanStefan Matthias Pulst
9
International Journal of Epidemiology

The association of urine metals and metal mixtures with cardiovascular incidence in an adult population from Spain: the Hortega Follow-Up Study

International Journal of EpidemiologyApril 9, 2019
Arce Domingo-RellosoMaria Tellez-Plaza
Scientific Reports

Different Grp94 components interact transiently with the myocilin olfactomedin domain in vitro to enhance or retard its amyloid aggregation

Scientific ReportsSeptember 4, 2019
Dustin J E HuardRaquel L. Lieberman
Nature Reviews. Neurology

Apolipoprotein E and Alzheimer disease: pathobiology and targeting strategies

Nature Reviews. NeurologyInvalid date
Yu YamazakiGuojun Bu
54
2
3
89
Circulation. Genomic and Precision Medicine

Biallelic Variants in ASNA1 , Encoding a Cytosolic Targeting Factor of Tail-Anchored Proteins, Cause Rapidly Progressive Pediatric Cardiomyopathy

Circulation. Genomic and Precision MedicineAugust 29, 2019
Judith M A VerhagenIngrid M B H van de Laar
1
Advances in Experimental Medicine and Biology

Recent Advances in Targeting Human Mitochondrial AAA+ Proteases to Develop Novel Cancer Therapeutics

Advances in Experimental Medicine and BiologyJanuary 1, 2019
Keith S Wong, Walid A Houry
Neural Regeneration Research

Potential therapeutic roles of retinoids for prevention of neuroinflammation and neurodegeneration in Alzheimer's disease

Neural Regeneration ResearchJuly 11, 2019
Bhaskar C DasSwapan Kumar Ray
3
1
21
ELife

Mitochondria supply ATP to the ER through a mechanism antagonized by cytosolic Ca2

ELifeSeptember 9, 2019
Jing YongRandal J. Kaufman
114
Chemical Science

Residue-specific identification of phase separation hot spots of Alzheimer's-related protein tau

Chemical ScienceJuly 14, 2019
Susmitha AmbadipudiMarkus Zweckstetter
1
19
European Journal of Medicinal Chemistry

An overview on chemical structures as ΔF508-CFTR correctors

European Journal of Medicinal ChemistryJuly 22, 2019
Virginia SpanòPaola Barraja
PLoS Pathogens

Development of a new largely scalable in vitro prion propagation method for the production of infectious recombinant prions for high resolution structural studies

PLoS PathogensOctober 23, 2019
Hasier ErañaJoaquín Castilla
12
Pakistan Journal of Pharmaceutical Sciences

Impacts of intake of bakery food chemicals, degraded water and psychiatric drugs on liver & renal functions of brain tumor patients

Pakistan Journal of Pharmaceutical SciencesJuly 1, 2019
Sana KhalidSajid Rasheed
Bioorganic & Medicinal Chemistry Letters

Synthesis of (R,S)-isoproterenol, an inhibitor of tau aggregation, as an 11 C-labeled PET tracer via reductive alkylation of (R,S)-norepinephrine with [2-11 C]acetone

Bioorganic & Medicinal Chemistry LettersJuly 3, 2019
Hiroshi IkenumaMasaaki Suzuki
1
1
Cell & Bioscience

The effect of the chemical chaperone 4-phenylbutyrate on secretion and activity of the p.Q160R missense variant of coagulation factor FVII

Cell & BioscienceAugust 27, 2019
Elisabeth AndersenGrethe Skretting
6
2
Bioorganic & Medicinal Chemistry

18 F-labeled benzimidazopyridine derivatives for PET imaging of tau pathology in Alzheimer's disease

Bioorganic & Medicinal ChemistryJuly 10, 2019
Sho KaideMasahiro Ono
1
2
Dementia and Geriatric Cognitive Disorders

In vivo Prevalence of Alzheimer Biomarkers in Dementia with Lewy Bodies

Dementia and Geriatric Cognitive DisordersJuly 16, 2019
George P ParaskevasElisabeth N Kapaki

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