Telomere Dysfunction

Telomere dysfunction in response to critical telomere shortening induces dna damage checkpoints that lead to cell cycle arrest and/or cell death.

January 21, 2022

Landscape of driver gene events, biomarkers, and druggable targets identified by whole-genome sequencing of glioblastomas.

Neuro-oncology Advances
Wesley S van de GeerFilip Y F de Vos
January 19, 2022

Genomic Correlates of Unfavorable Outcome in Locally Advanced Cervical Cancer Treated with Neoadjuvant Chemoradiation.

Cancer Research and Treatment : Official Journal of Korean Cancer Association
Yuchun WeiShuanghu Yuan
January 17, 2022
Open Access

Core promoter mutation contributes to abnormal gene expression in bladder cancer.

BMC Cancer
Teng HuangSan Ming Wang
January 16, 2022

Integrated analysis of ovarian juvenile granulosa cell tumors reveals distinct epigenetic signatures and recurrent TERT rearrangements.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
Theodore VougiouklakisGeorge Jour
January 15, 2022

Genome-wide screens identify specific drivers of mutant hTERT promoters.

Proceedings of the National Academy of Sciences of the United States of America
Raghuvaran ShanmugamVinay Tergaonkar
January 15, 2022

53BP1-shieldin-dependent DSB processing in BRCA1-deficient cells requires CST-Polα-primase fill-in synthesis.

Nature Cell Biology
Zachary MirmanTitia de Lange
January 14, 2022

TERT Promoter Mutations in Keratinizing and Nonkeratinizing Squamous Metaplasia of the Urinary Tract.

European Urology Open Science
Alexander S TaylorRohit Mehra
January 13, 2022

Frequent FGFR1 hotspot alterations in driver-unknown low-grade glioma and mixed neuronal-glial tumors.

Journal of Cancer Research and Clinical Oncology
Sophie EngelhardtJens Schittenhelm
January 12, 2022

Driver mutations in ADGRL3 are involved in the evolution of ependymoma.

Laboratory Investigation; a Journal of Technical Methods and Pathology
Jing WangZhong-Ping Chen
January 10, 2022

Molecular pathways and role of epigenetics in the idiopathic pulmonary fibrosis.

Life Sciences
Varalakshmi VelagacherlaUsha Yogendra Nayak
January 10, 2022

Solitary Fibrous Tumor With Extensive Epithelial Inclusions.

American Journal of Clinical Pathology
Ming ZhaoGuoqing Ru
January 11, 2022

Inherited human Apollo deficiency causes severe bone marrow failure and developmental defects.

Laëtitia KermassonPatrick Revy
January 6, 2022

Retinoblastoma protein regulates carcinogen susceptibility at heterochromatic cancer driver loci.

Life Science Alliance
Ka Man WongAshby J Morrison
January 6, 2022

FPIA: A database for gene fusion profiling and interactive analyses.

International Journal of Cancer. Journal International Du Cancer
Lu HuangYuanyan Xiong
January 6, 2022

New Era for Malignant Pleural Mesothelioma: Updates on Therapeutic Options.

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
Anne S TsaoAaron S Mansfield
January 5, 2022

Interstitial lung diseases associated with mutations of poly(A)-specific ribonuclease: A multicentre retrospective study.

Respirology : Official Journal of the Asian Pacific Society of Respirology
Quentin PhilippotOrphaLung Network

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