Feed Preview

Fast Growing

Telomere Dysfunction

Telomere Dysfunction diagram by Muñoz-Lorente et al, PLOS Genetics
Muñoz-Lorente et al, PLOS Genetics

Telomere dysfunction in response to critical telomere shortening induces dna damage checkpoints that lead to cell cycle arrest and/or cell death.

Top 20 most recent papers
Nature Genetics

Germline NPM1 mutations lead to altered rRNA 2'-O-methylation and cause dyskeratosis congenita

Nature GeneticsOctober 2, 2019
Daphna NachmaniPier Paolo Pandolfi
12
2
29
Nature Communications

Genomic landscape and chronological reconstruction of driver events in multiple myeloma

Nature CommunicationsAugust 25, 2019
Francesco MauraPeter J Campbell
18
50
bioRxiv

Revealing the impact of recurrent and rare structural variants in multiple myeloma

bioRxivDecember 19, 2019
Even H RustadFrancesco Maura
21
American Journal of Human Genetics

Genome Sequencing Explores Complexity of Chromosomal Abnormalities in Recurrent Miscarriage

American Journal of Human GeneticsNovember 5, 2019
Zirui DongZi-Jiang Chen
26
6
10
bioRxiv

Mechanisms Generating Cancer Genome Complexity From A Single Cell Division Error

bioRxivNovember 7, 2019
Neil UmbreitDavid Pellman
23
8
bioRxiv

Comprehensive molecular characterization of pediatric treatment-induced high-grade glioma: A distinct entity despite disparate etiologies with defining molecular characteristics and potential therapeutic targets

bioRxivOctober 25, 2019
John DeSistoAdam L. Green
11
1
bioRxiv

Chromosomal rearrangements and loss of subtelomeric adhesins linked to clade-specific phenotypes in Candida auris

bioRxivSeptember 5, 2019
José F MuñozChristina A Cuomo
36
7
British Journal of Cancer

DKC1 enhances angiogenesis by promoting HIF-1α transcription and facilitates metastasis in colorectal cancer

British Journal of CancerDecember 21, 2019
Pingfu HouJun Song
1
bioRxiv

Novel patterns of complex structural variation revealed across thousands of cancer genome graphs

bioRxivNovember 9, 2019
Kevin HadiMarcin Imielinski
163
31
ERJ Open Research

Prognostic significance of pulmonary function tests in dyskeratosis congenita, a telomere biology disorder

ERJ Open ResearchNovember 23, 2019
Neelam GiriSharon A Savage
15
1
1
Haematologica

DKC1 is a transcriptional target of GATA1 and drives upregulation of telomerase activity in normal human erythroblasts

HaematologicaAugust 16, 2019
Laura A RichardsKaren L MacKenzie
6
3
Cancer Genetics

Concurrent chromothripsis events in a case of TP53 depleted acute myeloid leukemia with myelodysplasia-related changes

Cancer GeneticsAugust 27, 2019
D TolomeoC T Storlazzi
Stem Cell Research

Telomere dynamics and hematopoietic differentiation of human DKC1-mutant induced pluripotent stem cells

Stem Cell ResearchSeptember 4, 2019
Flavia S DonairesRodrigo T Calado
2
4
Current Opinion in Oncology

Novel molecular targets for the treatment of lung cancer

Current Opinion in OncologyOctober 11, 2019
Rafael RosellOscar Arrieta
2
2
Mayo Clinic Proceedings

Dyskeratosis Congenita

Mayo Clinic ProceedingsSeptember 6, 2019
Eric T Stoopler, Rabie M Shanti
2
1
Neurology. Genetics

CNS manifestations in patients with telomere biology disorders

Neurology. GeneticsDecember 25, 2019
Sonia BhalaSharon A Savage
19
2
bioRxiv

GRIDSS, PURPLE, LINX: Unscrambling the tumor genome via integrated analysis of structural variation and copy number

bioRxivSeptember 25, 2019
Daniel L CameronPeter Priestley
46
11
Orvosi hetilap

The complex dental and oral surgical management with 8-year follow up of a Gorlin‒Goltz syndrome patient

Orvosi hetilapJanuary 7, 2020
Zsuzsanna GurdánJózsef Szalma
Journal of Clinical Medicine

Telomere Abnormalities in the Pathobiology of Idiopathic Pulmonary Fibrosis

Journal of Clinical MedicineAugust 21, 2019
Hasancan BilgiliWojciech J Piotrowski
Nature Cell Biology

The NSL complex maintains nuclear architecture stability via lamin A/C acetylation

Nature Cell BiologyOctober 3, 2019
Adam KaroutasAsifa Akhtar
50
3
41
1

See more papers from this feed

Related Feeds

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Artificial Chromosomes

Artificial chromosomes are genetically engineered chromosomes derived from the DNA of a species. Discover the latest research on artificial chromosomes here.

Biodiversity Data

Biodiversity refers to the variety and variability of life on Earth. Biodiversity is typically a measure of variation at the genetic, species, and ecosystem level.Discover the latest research on biodiversity data here.

Bioinformatics in Biomedicine

Bioinformatics in biomedicine incorporates computer science, biology, chemistry, medicine, mathematics and statistics. Discover the latest research on bioinformatics in biomedicine here.

CRISPR & Single Cell Analyses

CRISPR-Cas system enables the editing of genes to create or correct mutations. This feed focuses on CRISPR-Cas applications relevant to single cell analyses. Here is the latest research.

CRISPR & Staphylococcus

CRISPR-Cas system enables the editing of genes to create or correct mutations. Staphylococci are associated with life-threatening infections in hospitals, as well as the community. Here is the latest research on how CRISPR-Cas system can be used for treatment of Staphylococcal infections.

CRISPR (general)

Clustered regularly interspaced short palindromic repeats (CRISPR) are DNA sequences in the genome that are recognized and cleaved by CRISPR-associated proteins (Cas). CRISPR-Cas system enables the editing of genes to create or correct mutations. Discover the latest research on CRISPR here.

CRISPR Genome Editing & Therapy

CRISPR-Cas system enables the editing of genes to create or correct mutations. This feed focuses on the application of this system for gene editing and therapy in human diseases.

CRISPR Ribonucleases Deactivation

CRISPR-Cas system enables the editing of genes to create or correct mutations. This feed focuses on mechanisms that underlie deactivation of CRISPR ribonucleases. Here is the latest research.

CRISPR Screens in Drug Resistance

CRISPR-Cas system enables the editing of genes to create or correct mutations. This feed focuses on the application of CRISPR-Cas system in high-throughput genome-wide screens to identify genes that may confer drug resistance.

© 2020 Meta ULC. All rights reserved
/feed-previews/telomere-dysfunction/d2099185-fc64-4e5a-a4be-caac94b23dd1