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Telomere Dysfunction

Telomere Dysfunction diagram by Muñoz-Lorente et al, PLOS Genetics
Muñoz-Lorente et al, PLOS Genetics

Telomere dysfunction in response to critical telomere shortening induces dna damage checkpoints that lead to cell cycle arrest and/or cell death.

Top 20 most recent papers
Nature Genetics

Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing

Nature GeneticsFebruary 7, 2020
Isidro Cortés-CirianoPCAWG Consortium
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3
1
American Journal of Human Genetics

Genome Sequencing Explores Complexity of Chromosomal Abnormalities in Recurrent Miscarriage

American Journal of Human GeneticsNovember 5, 2019
Zirui DongZi-Jiang Chen
25
6
14
99
6
Nature Protocols

Analysis pipelines for cancer genome sequencing in mice

Nature ProtocolsJanuary 8, 2020
Sebastian LangeRoland Rad
5
Translational Lung Cancer Research

Chromosomal rearrangements and their neoantigenic potential in mesothelioma

Translational Lung Cancer ResearchMarch 25, 2020
Aaron Scott MansfieldGeorge Vasmatzis
Nature

Pan-cancer analysis of whole genomes

NatureFebruary 7, 2020
ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium
1567
39
14
1
4
Genes & Development

53BP1: a DSB escort

Genes & DevelopmentJanuary 4, 2020
Zachary Mirman, Titia de Lange
17
Molecular Genetics and Genomics : MGG

Genome-wide somatic copy number alteration analysis and database construction for cervical cancer

Molecular Genetics and Genomics : MGGJanuary 7, 2020
Hong LuoHaoyang Cai
Current Opinion in Genetics & Development

Chromothripsis and telomere crisis: engines of genome instability

Current Opinion in Genetics & DevelopmentMarch 11, 2020
Sally M Dewhurst
Current Opinion in Genetics & Development

Genome rearrangements associated with aberrant telomere maintenance

Current Opinion in Genetics & DevelopmentMarch 8, 2020
Ragini BhargavaRoderick J O'Sullivan
Molecular Cytogenetics

Chromoanagenesis: a piece of the macroevolution scenario

Molecular CytogeneticsFebruary 5, 2020
Franck Pellestor, Vincent Gatinois

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