Telomeres & Cell Cycle Checkpoint

Specialized telomeric proteins, as well as DNA repair and checkpoint proteins with a dual role in telomere maintenance and DNA damage signaling/repair, protect telomere ends from degradation. Here is the latest research on telomeres and cell cycle checkpoints.

November 28, 2021
Review
Open Access

Cell Cycle, Telomeres, and Telomerase in Leishmania spp.: What Do We Know So Far?

Cells
Luiz H C AssisMaria Isabel N Cano
November 22, 2021
Open Access

Telomerase subunit Est2 marks internal sites that are prone to accumulate DNA damage.

BMC Biology
Satyaprakash PandeyKatrin Paeschke
November 15, 2021

Characterization of the telomerase modulating activities of yeast DNA helicases.

Methods in Enzymology
David G Nickens, Matthew L Bochman
November 14, 2021

Molecular analysis of 10 pleomorphic rhabdomyosarcomas reveals potential prognostic markers and druggable targets.

Genes, Chromosomes & Cancer
Zachary L ChelskyEleanor Y Chen
November 14, 2021
Open Access

Molecular Consequences of Depression Treatment: A Potential In Vitro Mechanism for Antidepressants-Induced Reprotoxic Side Effects.

International Journal of Molecular Sciences
Przemysław SołekMarek Koziorowski
November 9, 2021
Review
Open Access

Senescence-Associated Secretory Phenotype as a Hinge Between Cardiovascular Diseases and Cancer.

Frontiers in Cardiovascular Medicine
Priyanka BanerjeeNhat-Tu Le
November 7, 2021

NF1-mutated melanomas reveal distinct clinical characteristics depending on tumour origin and respond favourably to immune checkpoint inhibitors.

European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)
Carl M ThielmannKlaus G Griewank
November 2, 2021

Homologous recombination-mediated irreversible genome damage underlies telomere-induced senescence.

Nucleic Acids Research
Sabrina GhadaouiaFrancis Rodier
November 1, 2021

Suppression of telomere capping defects of Saccharomyces cerevisiae yku70 and yku80 mutants by telomerase.

G3 : Genes - Genomes - Genetics
Cory L HollandL Kevin Lewis
October 30, 2021

DNA damage and aging on hematopoietic stem cells: Impact of oxidative stress in ApoE-/- mice.

Experimental Gerontology
R AiresS S Meyrelles
October 26, 2021
Open Access

Aggregation-induced emission luminogens reveal cell cycle-dependent telomerase activity in cancer cells.

National Science Review
Xia WuFan Xia
October 23, 2021

Primary high-grade serous ovarian cancer cells are sensitive to senescence induced by carboplatin and paclitaxel in vitro.

Cellular & Molecular Biology Letters
Paweł UruskiKrzysztof Książek

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