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TFIIH & Transcription (Keystone)

TFIIH & Transcription (Keystone) diagram by undefined

Transcription factor II human (TFIIH) is an important protein complex with roles in transcription of several protein-coding genes as well as in the nucleotide excision repair pathway. Here is the latest research relating to Dylan J. Taatjes' talk on new model for TFIIH function in transcription.

Top 20 most recent papers
Cancer Cell

CDK7 Inhibition Potentiates Genome Instability Triggering Anti-tumor Immunity in Small Cell Lung Cancer

Cancer CellDecember 31, 2019
Hua ZhangKwok-Kin Wong
88
1
bioRxiv

Disruption of TFIIH activities generates a stress gene expression response and reveals possible new targets against cancer

bioRxivDecember 3, 2019
Maritere Uriostegui ArcosMario Zurita
6
American Journal of Human Genetics

Bi-allelic TARS Mutations Are Associated with Brittle Hair Phenotype

American Journal of Human GeneticsAugust 3, 2019
Arjan F TheilDonata Orioli
Molecular Cell

Transcriptional Responses to IFN-γ Require Mediator Kinase-Dependent Pause Release and Mechanistically Distinct CDK8 and CDK19 Functions

Molecular CellSeptember 10, 2019
Iris SteinparzerPavel Kovarik
24
31
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research

Targeting super-enhancer-associated oncogenes in osteosarcoma with THZ2, a covalent CDK7 inhibitor

Clinical Cancer Research : an Official Journal of the American Association for Cancer ResearchJanuary 16, 2020
Jiajun ZhangJingnan Shen
2
bioRxiv

Structural basis of TFIIH activation for nucleotide excision repair

bioRxivMay 7, 2019
Goran KokicPatrick Cramer
41
6
Sub-cellular Biochemistry

The Structures of Eukaryotic Transcription Pre-initiation Complexes and Their Functional Implications

Sub-cellular BiochemistryJanuary 16, 2020
Basil J Greber, Eva Nogales
8
World Neurosurgery

Approach to Slit-like Ventricles: Parietal-Occipital vs. Frontal burr Catheter Entry Sites

World NeurosurgeryDecember 18, 2019
Claudia L CravenAhmed K Toma
bioRxiv

Suppression of p53 response by targeting p53-Mediator binding with a stapled peptide

bioRxivSeptember 4, 2019
Ben L AllenDylan J Taatjes
4
1
International Journal of Molecular Sciences

Drosophila as a Model Organism to Understand the Effects during Development of TFIIH-Related Human Diseases

International Journal of Molecular SciencesJanuary 23, 2020
Mario Zurita, Juan Manuel Murillo-Maldonado
1
Nature Communications

Structural basis of TFIIH activation for nucleotide excision repair

Nature CommunicationsJune 30, 2019
Goran KokicPatrick Cramer
32
40
1
Scientific Reports

The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair

Scientific ReportsApril 27, 2019
Steven E GuardWilliam M Old
4
28
bioRxiv

The Establishment of CDK9/ RNA PolII/H3K4me3/DNA Methylation Feedback Promotes HOTAIR Expression by RNA Elongation Enhancement in Cancer

bioRxivOctober 21, 2019
Chi Hin WongYangchao Chen
3
Cell Chemical Biology

Precision Retargeting: A Selective Covalent Inhibitor Illuminates CDK7 Biology

Cell Chemical BiologyJune 22, 2019
Lyn H Jones
bioRxiv

The TFIIH subunits p44/p62 act as a damage sensor during nucleotide excision repair

bioRxivMay 21, 2019
Jamie T BarnettNeil M Kad
17
1
Nature Communications

TFIIE orchestrates the recruitment of the TFIIH kinase module at promoter before release during transcription

Nature CommunicationsMay 9, 2019
Emmanuel CompeJean-Marc Egly
4
21
International Journal of Molecular Medicine

L‑carnitine alleviates oxidative stress‑related damage via MAPK signaling in human lens epithelial cells exposed to H2O2

International Journal of Molecular MedicineAugust 1, 2019
Xiaoxia LiXiaoyong Yuan
The Plant Journal : for Cell and Molecular Biology

Gene modification by fast-track recombineering for cellular localization and isolation of components of plant protein complexes

The Plant Journal : for Cell and Molecular BiologyJuly 6, 2019
Zhoubo HuCsaba Koncz
2
6
Cancer Letters

Combinational therapeutic targeting of BRD4 and CDK7 synergistically induces anticancer effects in head and neck squamous cell carcinoma

Cancer LettersNovember 26, 2019
Wei ZhangJie Cheng
European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

Immunohistochemical expression of TFIIH and XPF in oral tongue squamous cell carcinoma

European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck SurgeryDecember 13, 2019
Melka Coêlho SáRoseana de Almeida Freitas

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