Neurodegeneration: Therapeutic Targets

Neurodegeneration is the progressive loss of structure or function of neurons, including neuronal death, and leads to several diseases, including Alzheimer’s and Parkinson’s. This feed focuses on therapeutic targets for neurodegenerative disorders.

November 11, 2019

DNA double-strand breaks: a potential therapeutic target for neurodegenerative diseases

Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology
Nidheesh ThadathilMohammad Moshahid Khan
November 9, 2019

Butyrylcholinesterase: A Multifaceted Pharmacological Target and Tool.

Current Protein & Peptide Science
Zhe Ying HaKeng Yoon Yeong
March 14, 2020
Open Access

Protein Phosphatase 2A as a Drug Target in the Treatment of Cancer and Alzheimer's Disease

Current Medical Science
Hui WeiRong Liu
June 9, 2020
Open Access

Molecular Insight into the Therapeutic Promise of Targeting APOE4 for Alzheimer's Disease

Oxidative Medicine and Cellular Longevity
Abdullah Al MamunMohamed M Abdel-Daim
July 12, 2019
Case Report
Open Access

Atopic Dermatitis-Like Rash During Evolocumab Treatment of Familial Hypercholesterolemia

Journal of Nippon Medical School = Nippon Ika Daigaku Zasshi
Naoko Kanda, Fumitaka Okajima
June 23, 2019
Open Access

Recent advances in molecular therapies for neurological disease: triplet repeat disorders

Human Molecular Genetics
Pedro Gonzalez-Alegre
November 21, 2019

Destabilization of β-amyloid aggregates by thrombin derived peptide: plausible role of thrombin in neuroprotection

The FEBS Journal
Debashree DeDebasish Bhattacharyya
June 28, 2019

The Outliers: Metal-Mediated Radical Reagents for Biological Substrate Degradation

Accounts of Chemical Research
Meghan R PorterJeffrey M Zaleski
April 20, 2020
Open Access

Cathepsin B in neurodegeneration of Alzheimer's disease, traumatic brain injury, and related brain disorders

Biochimica Et Biophysica Acta. Proteins and Proteomics
Vivian HookGregory Hook
June 9, 2020
Open Access

Inhibition of STAT3 phosphorylation attenuates impairments in learning and memory in 5XFAD mice, an animal model of Alzheimer's disease

Journal of Pharmacological Sciences
Moonseok ChoiHye-Sun Kim
May 12, 2020

Inherited disorders of lysosomal membrane transporters

Biochimica Et Biophysica Acta. Biomembranes
Marjan Huizing, William A Gahl
September 27, 2019
Open Access

A New Kid on the Block? Carbonic Anhydrases as Possible New Targets in Alzheimer's Disease

International Journal of Molecular Sciences
Gustavo ProvensiSilvia Fossati
December 17, 2019
Open Access

Tau as a potential therapeutic target for ischemic stroke

Xin Chen, Hua Jiang
December 8, 2019
Open Access

Mechanisms of immune evasion in bladder cancer

Cancer Immunology, Immunotherapy : CII
Paul L Crispen, Sergei Kusmartsev
June 5, 2019

Recent Developments in LRRK2-Targeted Therapy for Parkinson's Disease

Ye Zhao, Nicolas Dzamko
November 22, 2019
Open Access

Vitamin K1 As A Potential Molecule For Reducing Single-Walled Carbon Nanotubes-Stimulated α-Synuclein Structural Changes And Cytotoxicity

International Journal of Nanomedicine
Amitis NaskhiMojtaba Falahati

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