Therapeutic Targets For Neurodegeneration

Neurodegeneration is the progressive loss of structure or function of neurons, including neuronal death, and leads to several diseases, including Alzheimer’s and Parkinson’s. This feed focuses on therapeutic targets for neurodegenerative disorders.

October 12, 2019

From Yeast to Humans: Leveraging New Approaches in Yeast to Accelerate Discovery of Therapeutic Targets for Synucleinopathies

Methods in Molecular Biology
Jeff S Piotrowski, Daniel F Tardiff
July 28, 2020
Open Access

Flavonoids as Potential Drugs for VPS13 -Dependent Rare Neurodegenerative Diseases

Genes
Piotr SoczewkaTeresa Zoladek
September 25, 2019
Open Access

Phosphorylation of mitochondrial matrix proteins regulates their selective mitophagic degradation

Proceedings of the National Academy of Sciences of the United States of America
Panagiota KolitsidaHagai Abeliovich
July 14, 2020
Comment / Editorial
Open Access

Hiding in plain sight: vesicle-mediated export and transmission of prion-like proteins

Microbial Cell
Mehdi Kabani
October 6, 2019
Open Access

Genetic Screens to Study GAA/TTC and Inverted Repeat Instability in Saccharomyces cerevisiae

Methods in Molecular Biology
Wenying Guo, Kirill S Lobachev
August 11, 2019
Open Access

The prion-like protein kinase Sky1 is required for efficient stress granule disassembly

Nature Communications
Jenifer E ShattuckEric D Ross
November 11, 2019
Review

DNA double-strand breaks: a potential therapeutic target for neurodegenerative diseases

Chromosome Research : an International Journal on the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology
Nidheesh ThadathilMohammad Moshahid Khan
January 18, 2020

Effect of tetracycline family of antibiotics on actin aggregation, resulting in the formation of Hirano bodies responsible for neuropathological disorders

Journal of Biomolecular Structure & Dynamics
Samridhi PathakAvinash Kale
November 21, 2019

Destabilization of β-amyloid aggregates by thrombin derived peptide: plausible role of thrombin in neuroprotection

The FEBS Journal
Debashree DeDebasish Bhattacharyya
June 9, 2020
Open Access

Inhibition of STAT3 phosphorylation attenuates impairments in learning and memory in 5XFAD mice, an animal model of Alzheimer's disease

Journal of Pharmacological Sciences
Moonseok ChoiHye-Sun Kim
May 12, 2020
Review

Inherited disorders of lysosomal membrane transporters

Biochimica Et Biophysica Acta. Biomembranes
Marjan Huizing, William A Gahl
September 27, 2019
Review
Open Access

A New Kid on the Block? Carbonic Anhydrases as Possible New Targets in Alzheimer's Disease

International Journal of Molecular Sciences
Gustavo ProvensiSilvia Fossati
December 8, 2019
Review
Open Access

Mechanisms of immune evasion in bladder cancer

Cancer Immunology, Immunotherapy : CII
Paul L Crispen, Sergei Kusmartsev
November 22, 2019
Open Access

Vitamin K1 As A Potential Molecule For Reducing Single-Walled Carbon Nanotubes-Stimulated α-Synuclein Structural Changes And Cytotoxicity

International Journal of Nanomedicine
Amitis NaskhiMojtaba Falahati
October 16, 2019
Review
Open Access

Clinical drug development for dementia with Lewy bodies: past and present

Expert Opinion on Investigational Drugs
Garam LeeMarwan N Sabbagh
November 1, 2019

Structure and Regulation of Glycogen Synthase in the Brain

Advances in Neurobiology
Bartholomew A Pederson
March 5, 2020
Open Access

Composition-based prediction and rational manipulation of prion-like domain recruitment to stress granules

Proceedings of the National Academy of Sciences of the United States of America
Amy E BoncellaEric D Ross

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