Trans-NIH Pediatric Research Consortium

The Trans-NIH Pediatric Research Consortium coordinates the pediatric research programs funded by NIH to promote collaboration, explore gaps and opportunities in the NIH pediatric research portfolio. Follow this feed to stay up to date on publications from this institute.

July 2, 2020

Current status of MEK inhibitors in the treatment of plexiform neurofibromas

Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery
Andrea M GrossBrigitte C Widemann
May 26, 2020

Pulmonary Function in Patients with Multiple Endocrine Neoplasia 2B (MEN2B)

The Journal of Clinical Endocrinology and Metabolism
Sarah FullerJohn Glod
April 17, 2020
Open Access

National Heart, Lung, and Blood Institute cardiovascular clinical trial perspective

American Heart Journal
Gail D PearsonDavid C Goff
June 26, 2020

Safety and efficacy of 48 and 96 weeks of alendronate in children and adolescents with perinatal HIV infection and low bone mineral density for age

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
J C LindseyIMPAACT P1076 Study Team
February 8, 2020
Open Access

Down syndrome

Nature Reviews. Disease Primers
Stylianos E AntonarakisRoger H Reeves
May 18, 2020
Open Access

PRMT1 promotes neuroblastoma cell survival through ATF5

Zhong-Yan HuaXing-Guo Li
July 1, 2020
Comment / Editorial

The 2019 Malcolm Ferguson-Smith Young Investigator Award

Prenatal Diagnosis
Diana W BianchiSarah Tatum George
March 19, 2020
Clinical Trial

Selumetinib in Children with Inoperable Plexiform Neurofibromas

The New England Journal of Medicine
Andrea M GrossBrigitte C Widemann
September 15, 2020


Journal of Acquired Immune Deficiency Syndromes : JAIDS
Diana F ClarkeInternational Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) P1097 Study Team
September 3, 2020

Case 2: Delayed Puberty in a 15-year-old Girl

Pediatrics in Review
Helen K HughesKatherine Beckwith-Fickas
March 18, 2020

Challenges and lessons learned from the Pediatric Heart Network Normal Echocardiogram Database study

Cardiology in the Young
Dongngan TruongPediatric Heart Network Investigators
August 21, 2020
Open Access

Early Life Experiences and Trajectories of Cognitive Development

July 4, 2020

Fractures in children and adolescents living with perinatally acquired HIV

Denise L JacobsonPediatric HIV/AIDS Cohort Study
June 18, 2020
Open Access

Protections against the Risk of Airborne SARS-CoV-2 Infection

Clement J McDonald
July 1, 2020

A molecular basis for neurofibroma-associated skeletal manifestations in NF1

Genetics in Medicine : Official Journal of the American College of Medical Genetics
Yun MaFlorent Elefteriou
August 17, 2020
Open Access

Targeting Vitamin-D receptor (VDR) by a small molecule antagonist MeTC7 inhibits PD-L1 but controls THMYCN neuroblastoma growth PD-L1 independently

BioRxiv : the Preprint Server for Biology
Rakesh K SinghR. Moore
July 1, 2020
Open Access

Stochastic Analysis Probes the Role of the Chaperone Hfq in E. coli Sugar Shock Response

BioRxiv : the Preprint Server for Biology
D. M. BianchiZaida Luthey-Schulten
July 30, 2020
Open Access

Raltegravir use and outcomes among children and adolescents living with HIV in the IeDEA global consortium

Journal of the International AIDS Society
Gabriela PattenIeDEA

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STING Receptor Agonists

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LRRK2 & Immunity During Infection

Mutations in the LRRK2 gene are a risk-factor for developing Parkinson’s disease. However, LRRK2 has been shown to function as a central regulator of vesicular trafficking, infection, immunity, and inflammation. Here is the latest research on the role of this kinase on immunity during infection.

Antiphospholipid Syndrome

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Meningococcal Myelitis

Meningococcal myelitis is characterized by inflammation and myelin damage to the meninges and spinal cord. Discover the latest research on meningococcal myelitis here.

Alzheimer's Disease: MS4A

Variants within membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease by recent genome-wide association studies. Here is the latest research.

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