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Transcription and Motor Neurons

Transcription and Motor Neurons diagram by Hideyama et al, PLOS One
Hideyama et al, PLOS One

Motor neurons innervate muscles as a part of the peripheral nervous system and are responsible for both autonomic and volitional movement. Find the latest research on transcription in motor neurons here.

Top 20 most recent papers

Correction of amyotrophic lateral sclerosis related phenotypes in induced pluripotent stem cell-derived motor neurons carrying a hexanucleotide expansion mutation in C9orf72 by CRISPR/Cas9 genome editing using homology-directed repair

bioRxivDecember 20, 2019
Nidaa AbabnehKevin Talbot

Hox binding specificity is directed by DNA sequence preferences and differential abilities to engage inaccessible chromatin.

bioRxivDecember 30, 2019
Milica BulajicEsteban O Mazzoni

Species-specific developmental timing is associated with global differences in protein stability in mouse and human

bioRxivDecember 31, 2019
Teresa RayonJames Briscoe

Characterization of human-iPSCs derived spinal motor neurons by single-cell RNA sequencing

bioRxivDecember 28, 2019
Louise ThiryStefano Stifani
Disease Models & Mechanisms

Modelling the pathogenesis of X-linked distal hereditary motor neuropathy using patient-derived iPSCs

Disease Models & MechanismsJanuary 24, 2020
Gonzalo Perez-SilesMarina L Kennerson
Experimental and Therapeutic Medicine

STAT3 speeds up progression of osteoarthritis through NF-κB signaling pathway

Experimental and Therapeutic MedicineDecember 31, 2019
Feida WangYinpeng Yuan
Scientific Reports

Onecut-dependent Nkx6.2 transcription factor expression is required for proper formation and activity of spinal locomotor circuits

Scientific ReportsJanuary 24, 2020
Mathilde TochFrédéric Clotman
International Journal of Biological Sciences

Nicotinamide Riboside Enhances Mitochondrial Proteostasis and Adult Neurogenesis through Activation of Mitochondrial Unfolded Protein Response Signaling in the Brain of ALS SOD1G93A Mice

International Journal of Biological SciencesJanuary 14, 2020
Qi ZhouRenshi Xu
Hearing Research

Generation of a ChATCre mouse line without the early onset hearing loss typical of the C57BL/6J strain

Hearing ResearchJanuary 27, 2020
Nichole L BeebeBrett R Schofield
Neurochemical Research

Glial Factors Regulating White Matter Development and Pathologies of the Cerebellum

Neurochemical ResearchJanuary 25, 2020
Miren RevueltaThomas Schmitz
Advanced Science

Leaky Optoelectrical Fiber for Optogenetic Stimulation and Electrochemical Detection of Dopamine Exocytosis from Human Dopaminergic Neurons

Advanced ScienceDecember 25, 2019
Shashank VasudevanJenny Emnéus
International Journal of Molecular Sciences

Stem Cells Therapy for Spinal Cord Injury: An Overview of Clinical Trials

International Journal of Molecular SciencesJanuary 23, 2020
Serena SilvestroEmanuela Mazzon
Acta Neuropathologica Communications

A robust TDP-43 knock-in mouse model of ALS

Acta Neuropathologica CommunicationsJanuary 23, 2020
Shih-Ling HuangChe-Kun James Shen
Expert Opinion on Drug Discovery

Organoid and pluripotent stem cells in Parkinson's disease modeling: an expert view on their value to drug discovery

Expert Opinion on Drug DiscoveryJanuary 5, 2020
Nick MarottaDimitri Krainc
Tissue Engineering and Regenerative Medicine

Combination of Human Mesenchymal Stem Cells and Repetitive Transcranial Magnetic Stimulation Enhances Neurological Recovery of 6-Hydroxydopamine Model of Parkinsonian's Disease

Tissue Engineering and Regenerative MedicineJanuary 24, 2020
Ji Yong LeeByung Pil Cho
The Cochrane Database of Systematic Reviews

Cell-based therapies for amyotrophic lateral sclerosis/motor neuron disease

The Cochrane Database of Systematic ReviewsDecember 20, 2019
S Fadilah Abdul WahidNai Ming Lai
Molecular Therapy. Methods & Clinical Development

Non-toxic HSC Transplantation-Based Macrophage/Microglia-Mediated GDNF Delivery for Parkinson's Disease

Molecular Therapy. Methods & Clinical DevelopmentJanuary 1, 2020
Cang ChenSenlin Li
Stem Cell Research & Therapy

Bone marrow-derived neural crest precursors improve nerve defect repair partially through secreted trophic factors

Stem Cell Research & TherapyDecember 20, 2019
Haiyan ShiFei Ding

Schwann cells orchestrate peripheral nerve inflammation through the expression of CSF1, IL-34, and SCF in amyotrophic lateral sclerosis

GliaDecember 21, 2019
Emiliano TriasLuis Barbeito
Nature Protocols

On-chip 3D neuromuscular model for drug screening and precision medicine in neuromuscular disease

Nature ProtocolsJanuary 15, 2020
Tatsuya OsakiRoger D Kamm

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