tRNA synthetases

Aminoacyl-tRNA synthetases, also known as tRNA-ligases, are enzymes that attaches the appropriate amino acid onto its transfer RNA. Mutations in these enzymes have been linked to several diseases including Charcot-Marie-Tooth and cancer. Here is the latest research.

August 26, 2020

Metabolic stress promotes stop-codon readthrough and phenotypic heterogeneity

Proceedings of the National Academy of Sciences of the United States of America
Hong ZhangJiqiang Ling
September 18, 2020
Open Access

Evidence for a dominant-negative mechanism in HARS1-mediated peripheral neuropathy

The FEBS Journal
Rebecca Meyer-Schuman, Anthony Antonellis
September 9, 2020

Classification of idiopathic inflammatory myopathies based on clinical manifestations and myositis-specific antibodies

Nan fang yi ke da xue xue bao = Journal of Southern Medical University
Songyuan ZhengJuan Li
September 10, 2020
Open Access

Personalized Medicine for PLA2R1-Related Membranous Nephropathy: A Multicenter Randomized Control Trial

Frontiers in Medicine
Vesna BrglezBarbara Seitz-Polski
September 2, 2020
Open Access

Enzymatic Regulation and Biological Functions of Reactive Cysteine Persulfides and Polysulfides

Tomohiro SawaTakaaki Akaike
September 26, 2020

Functional genetic encoding of sulfotyrosine in mammalian cells

Nature Communications
Xinyuan HeWei Niu
September 22, 2020

Systematic Surgical Approach to Alar Base Surgery in Rhinoplasty

Plastic and Reconstructive Surgery
Rod J RohrichYash J Avashia
September 9, 2020

tRNA-dependent amide bond-forming enzymes in peptide natural product biosynthesis

Current Opinion in Chemical Biology
Chitose Maruyama, Yoshimitsu Hamano
August 22, 2020

On the origin of matrix mechanism in protocells and key problems of molecular biology

Journal of Biomolecular Structure & Dynamics
Eduard Y Kostetsky, Vladimir N Uversky
September 10, 2020

Anti-Ro52 antibody is an independent risk factor for interstitial lung disease in dermatomyositis

Respiratory Medicine
Xiaojing XingChengxin Li
August 28, 2020
Open Access

Altered Sensory Neuron Development in CMT2D Mice Is Site-Specific and Linked to Increased GlyRS Levels

Frontiers in Cellular Neuroscience
James N SleighGiampietro Schiavo

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