Tumor Immune Microenvironment

The tumor immune microenvironment (TIME) is composed of hetereogenous immune cells that have infiltrated the tumor, and is a central target of cancer immunotherapies. Characterization of the TIME is key to predicting response and development of immunotherapy. Discover the latest research here.

January 19, 2020
Review
Open Access

Immune biological rationales for the design of combined radio- and immunotherapies

Cancer Immunology, Immunotherapy : CII
Michael HaderUdo S Gaipl
December 19, 2019
Open Access

B7H4 expression in tumor cells impairs CD8 T cell responses and tumor immunity

Cancer Immunology, Immunotherapy : CII
Linlin ZhouQiuyu Zhang
February 20, 2020
Review

Molecular Mechanisms of Notch Signaling in Lymphoid Cell Lineages Development: NF-κB and Beyond

Advances in Experimental Medicine and Biology
G TsaouliM P Felli
December 28, 2019
Open Access

Transcriptome-based molecular subtyping of non-small cell lung cancer may predict response to immune checkpoint inhibitors

The Journal of Thoracic and Cardiovascular Surgery
Hee-Jin JangYoung Tae Kim
May 4, 2020

Identification of a regulatory Vδ1 gamma delta T cell subpopulation expressing CD73 in human breast cancer

Journal of Leukocyte Biology
Ghita ChababVirginie Lafont
January 17, 2020

Tertiary lymphoid structures improve immunotherapy and survival in melanoma

Nature
Rita CabritaGöran Jönsson
February 16, 2020
Review

IL-36 Signaling in the Tumor Microenvironment

Advances in Experimental Medicine and Biology
Manoj ChelvanambiWalter J Storkus
February 16, 2020
Review

CCL21 Programs Immune Activity in Tumor Microenvironment

Advances in Experimental Medicine and Biology
Sherven SharmaSteven Dubinett
February 16, 2020
Review

IL-21 Signaling in the Tumor Microenvironment

Advances in Experimental Medicine and Biology
Ghita ChababVirginie Lafont
April 15, 2020

Intratumoral B cells and tertiary lymphoid structures are biomarkers of survival and immunotherapy responses

Bulletin du cancer
Wolf Herman FridmanCatherine Sautès-Fridman
February 16, 2020
Review

CCL4 Signaling in the Tumor Microenvironment

Advances in Experimental Medicine and Biology
Naofumi MukaidaTomohisa Baba
December 14, 2019
Open Access

High intratumoural galectin-1 expression predicts adverse outcome in ALK- ALCL and CD30+ PTCL-NOS

Hematological Oncology
Johanne Marie HolstMartin Bjerregård Pedersen
January 10, 2020
Review

Gastroesophageal cancer: Navigating the immune and genetic terrain to improve clinical outcomes

Cancer Treatment Reviews
James O Jones, Elizabeth C Smyth
March 7, 2020

Complement C1q mediates the expansion of periportal hepatic progenitor cells in senescence-associated inflammatory liver

Proceedings of the National Academy of Sciences of the United States of America
Tung-Ching HoDing-Shinn Chen
March 7, 2020

Benefits of exercise and immunotherapy in a murine model of human non-small-cell lung carcinoma

Exercise Immunology Review
Asunción Martín-RuizAlejandro Lucia
January 5, 2020
Review
Open Access

Siglec-15: a potential regulator of osteoporosis, cancer, and infectious diseases

Journal of Biomedical Science
Takashi Angata
February 11, 2020
Review

Lymphatic Endothelial Cell Progenitors in the Tumor Microenvironment

Advances in Experimental Medicine and Biology
Sophia Ran, Lisa Volk-Draper

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