Ubiquitin System (Preprints)

Ubiquitin is a small regulatory protein that is attached to proteins as a post-translational modification in a process known as ubiquitination to regulate protein turnover, location, or activity. Here is the latest research on the ubiquitin system.

February 24, 2021
Preprint
Open Access

Biased removal and loading of centromeric histone H3 during reproduction underlies uniparental genome elimination

BioRxiv : the Preprint Server for Biology
M. P. A. MarimuthuLuca Comai
February 23, 2021
Preprint
Open Access

Arkadia-SKI/SnoN signaling cascade differentially regulates TGF-β-induced iTreg and Th17 cell differentiation

BioRxiv : the Preprint Server for Biology
H. XuDan R Littman
February 23, 2021
Preprint
Open Access

Histone H2Bub1 deubiquitylation is essential for mouse development, but does not regulate global RNA polymerase II transcription

BioRxiv : the Preprint Server for Biology
F. WangLaszlo Tora
February 22, 2021
Preprint
Open Access

Previously uncharacterized interactions between the folded and intrinsically disordered domains impart asymmetric effects on UBQLN2 phase separation

BioRxiv : the Preprint Server for Biology
T. Zheng, C. A. Castaneda
February 22, 2021
Preprint
Open Access

An Autoantigen Profile of Human A549 Lung Cells Reveals Viral and Host Etiologic Molecular Attributes of Autoimmunity in COVID-19

BioRxiv : the Preprint Server for Biology
J. Y. WangMichael H. Roehrl
February 22, 2021
Preprint
Open Access

Old players in new posts: the role of P53, ATM and DNAPK in DNA damage-related ubiquitylation-dependent removal of S2P RNAPII

BioRxiv : the Preprint Server for Biology
B. N. BorsosTibor Pankotai
February 22, 2021
Preprint
Open Access

The Antiviral Enzyme, Viperin, Activates Protein Ubiquitination by the E3 Ubiquitin Ligase, TRAF6

BioRxiv : the Preprint Server for Biology
A. M. Patel, Neil Marsh
February 21, 2021
Preprint
Open Access

TOR complex 2 promotes proteasome dependent Pub1 (NEDD4 family E3 ligase) turnover in fission yeast.

BioRxiv : the Preprint Server for Biology
T. WangJanni Petersen
February 18, 2021
Preprint
Open Access

Potent, Novel SARS-CoV-2 PLpro Inhibitors Block Viral Replication in Monkey and Human Cell Cultures.

BioRxiv : the Preprint Server for Biology
Zhengnan ShenRui Xiong
February 12, 2021
Preprint
Open Access

The C. elegans Notch proteins LIN-12 and GLP-1 are tuned to lower force thresholds for activation than Drosophila Notch

BioRxiv : the Preprint Server for Biology
P. D. LangridgeG. Struhl
February 10, 2021
Preprint
Open Access

RNF43 inhibits WNT5A driven signaling and suppresses melanoma invasion

BioRxiv : the Preprint Server for Biology
T. RadaszkiewiczVítězslav Bryja
February 10, 2021
Preprint
Open Access

Methylation of KRAS at lysine 182 and 184 by SETD7 promotes KRAS degradation

BioRxiv : the Preprint Server for Biology
C. ChiangD. Zheng
February 9, 2021
Preprint
Open Access

DNA damage-induced phosphorylation of histone H2A at serine 15 is linked to DNA end resection

BioRxiv : the Preprint Server for Biology
S. Ahmad, Jacques Cote
February 8, 2021
Preprint
Open Access

Mechanistic insight into substrate processing and allosteric inhibition of human p97

BioRxiv : the Preprint Server for Biology
M. PanMinglei Zhao
February 8, 2021
Preprint
Open Access

Neuronal activity promotes nuclear proteasome-mediated degradation of PDCD4 to regulate activity-dependent transcription

BioRxiv : the Preprint Server for Biology
W. A. HerbstKelsey C. Martin
February 7, 2021
Preprint
Open Access

NEDD4 Regulates Ubiquitination and Stability of the Cell adhesion Molecule IGPR-1 via Lysosomal Pathway

BioRxiv : the Preprint Server for Biology
L. SunNader Rahimi
February 6, 2021
Preprint
Open Access

G9a/GLP methyltransferases inhibit autophagy by methylation-mediated ATG12 protein degradation

BioRxiv : the Preprint Server for Biology
C.-H. KimK.-T. Park
February 4, 2021
Preprint
Open Access

Alpha-arrestins Aly1 and Aly2 regulate trafficking of the glycerophosphoinositol transporter Git1 and impact phospholipid homeostasis

BioRxiv : the Preprint Server for Biology
B. P. RobinsonAllyson F. O'Donnell
February 4, 2021
Preprint
Open Access

Mechanism of Viral Glycoprotein Targeting by Membrane-associated-RING-CH Proteins.

BioRxiv : the Preprint Server for Biology
C. M. LunEric O Freed
February 3, 2021
Preprint
Open Access

Extracellular matrix stiffness regulates degradation of the Hippo kinase MST2 via SCFβTrCP

BioRxiv : the Preprint Server for Biology
A. P. Z. P. FioreAlexandre Bruni-Cardoso

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