Ubiquitin System (Preprints)

Ubiquitin is a small regulatory protein that is attached to proteins as a post-translational modification in a process known as ubiquitination to regulate protein turnover, location, or activity. Here is the latest research on the ubiquitin system.

July 30, 2020
Preprint
Open Access

High-throughput identification of nuclear envelope protein interactions in Schizosaccharomyces pombe using an arrayed membrane yeast-two hybrid library

BioRxiv : the Preprint Server for Biology
J. M. VarbergSue L Jaspersen
September 4, 2020
Preprint
Open Access

Combinatorial native MS and LC-MS/MS approach reveals high intrinsic phosphorylation of human Tau but minimal levels of other key modifications

BioRxiv : the Preprint Server for Biology
F. DrepperEckhard Mandelkow
August 15, 2020
Preprint
Open Access

Nitric oxide prevents aortic valve calcification by S-nitrosylation of USP9X to activate NOTCH signaling

BioRxiv : the Preprint Server for Biology
U. MajumdarVidu Garg
August 13, 2020
Preprint
Open Access

Optineurin promotes aggregation of mutant huntingtin and mutant ataxin-3, and reduces cytotoxicity of aggregates

BioRxiv : the Preprint Server for Biology
S. C. MoharirGhanshyam Swarup
July 21, 2020
Preprint
Open Access

Regulated assembly of the ER membrane protein complex

BioRxiv : the Preprint Server for Biology
T. PleinerRebecca M Voorhees
August 19, 2020
Preprint
Open Access

Modular HUWE1 architecture serves as hub for degradation of cell-fate decision factors

BioRxiv : the Preprint Server for Biology
M. HunkelerEric S Fischer
July 29, 2020
Preprint
Open Access

Substrate-induced clustering activates Trim-Away of pathogens and proteins

BioRxiv : the Preprint Server for Biology
J. ZengLeo C James
July 18, 2020
Preprint
Open Access

Structural basis for the inhibition of the papain-like protease of SARS-CoV-2 by small molecules

BioRxiv : the Preprint Server for Biology
Z. FuHao Huang
August 21, 2020
Preprint
Open Access

An autonomous, but INSIG-modulated, role for the Sterol Sensing Domain in mallostery-regulated ERAD of yeast HMG-CoA reductase

BioRxiv : the Preprint Server for Biology
M. A. Wangeline, Randolph Y Hampton
July 24, 2020
Preprint
Open Access

Deep ubiquitination site profiling by single-shot data-independent acquisition mass spectrometry

BioRxiv : the Preprint Server for Biology
Martin StegerH. Daub
August 13, 2020
Preprint
Open Access

Shared and divergent phase separation and aggregation properties of brain-expressed ubiquilins

BioRxiv : the Preprint Server for Biology
J. E. GersonMagdalena I Ivanova
August 19, 2020
Preprint
Open Access

Aquaporin-3 regulates endosome-to-cytosol transfer via lipid peroxidation for cross presentation

BioRxiv : the Preprint Server for Biology
Sam NalleI. Mellman
July 22, 2020
Preprint
Open Access

Characterization of Plasmodium falciparum NEDD8 and identification of cullins as its substrates

BioRxiv : the Preprint Server for Biology
M. BhattacharjeePuran Singh Sijwali
July 28, 2020
Preprint
Open Access

Serine-ubiquitination regulates Golgi morphology and the secretory pathway upon Legionella infection

BioRxiv : the Preprint Server for Biology
Y. LiuIvan Dikic
July 29, 2020
Preprint
Open Access

PLEKHA4 Promotes Wnt/β-catenin Signaling-Mediated G1/S Transition and Proliferation in Melanoma

BioRxiv : the Preprint Server for Biology
A. Shami ShahJeremy M Baskin
July 26, 2020
Preprint
Open Access

Laminin N-terminus α31 expression during development in an inducible-transgenic mouse model is lethal and causes a multitude of tissue-specific defects

BioRxiv : the Preprint Server for Biology
C. J. SugdenKevin J Hamill
July 22, 2020
Preprint
Open Access

Crosstalk between chloroplast protein import and the SUMO system revealed through genetic and molecular investigation

BioRxiv : the Preprint Server for Biology
S. WatsonR. Paul Jarvis
August 22, 2020
Preprint
Open Access

The Deubiquitylase Ubp15 Couples Transcription to mRNA Export

BioRxiv : the Preprint Server for Biology
F. EybouletFrançois Robert

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