Ubiquitin System (Preprints)

Ubiquitin is a small regulatory protein that is attached to proteins as a post-translational modification in a process known as ubiquitination to regulate protein turnover, location, or activity. Here is the latest research on the ubiquitin system.

April 18, 2020
Preprint
Open Access

Phosphoproteomics Reveals a Distinct Mode of Mec1/ATR Signaling in Response to DNA End Hyper-Resection

BioRxiv : the Preprint Server for Biology
E. J. SanfordMarcus B. Smolka
May 15, 2020
Preprint
Open Access

Proteasome-mediated regulation of Cdhr1a by Siah1 modulates photoreceptor development and survival in zebrafish.

BioRxiv : the Preprint Server for Biology
W. PiedadeJakub Famulski
June 11, 2020
Preprint
Open Access

Global RNA-seq identified FBXL8 as a novel E3 ligase which modulates tumor suppressors to promote BRCA advancement

MedRxiv : the Preprint Server for Health Sciences
Shu-Chun ChangJ. L. Ding
June 26, 2020
Preprint
Open Access

Functional domain studies uncover novel roles for the ZTL Kelch repeat domain in clock function

BioRxiv : the Preprint Server for Biology
A. Feke, Joshua Gendron
June 2, 2020
Preprint
Open Access

Oxidative switch drives mitophagy defects in dopaminergic parkin mutant patient neurons

BioRxiv : the Preprint Server for Biology
A. SchwartzentruberHeather J Mortiboys
July 2, 2020
Preprint

6-Thioguanine blocks SARS-CoV-2 replication by inhibition of PLpro protease activities

BioRxiv : the Preprint Server for Biology
C. D. SwaimJon M. Huibregtse
July 6, 2020
Preprint

Scaled Recoupling of Chemical Shift Anisotropies at High Magnetic Fields under MAS with Interspersed C-elements

BioRxiv : the Preprint Server for Biology
K. J. FritzschingAnn E McDermott
May 27, 2020
Preprint
Open Access

Comparative analysis of macrophage post-translational modifications during intracellular bacterial pathogen infection

BioRxiv : the Preprint Server for Biology
J. R. JohnsonJ. S. Cox
March 19, 2020
Preprint
Open Access

Interaction mapping of endoplasmic reticulum ubiquitin ligases identifies modulators of innate immune signalling

BioRxiv : the Preprint Server for Biology
Emma J FenechJohn C Christianson
June 30, 2020
Preprint
Open Access

Klebsiella pneumoniae reduces SUMOylation to limit host defence responses

BioRxiv : the Preprint Server for Biology
J. Sa-PessoaJose A Bengoechea
June 22, 2020
Preprint
Open Access

PP1 promotes cyclin B destruction and the metaphase-anaphase transition by dephosphorylating CDC20

BioRxiv : the Preprint Server for Biology
J. BancroftUlrike Gruneberg
July 2, 2020
Preprint

SUV39 SET domains mediate crosstalk of heterochromatic histone marks

BioRxiv : the Preprint Server for Biology
A. StirpeS. Kilic
May 15, 2020
Preprint
Open Access

MEKK3-MEK5-ERK5 signaling promotes mitochondrial degradation

BioRxiv : the Preprint Server for Biology
J. E. CraigMalia B Potts
July 1, 2020
Preprint

An evolutionary approach to systematic discovery of novel deubiquitinases, applied to Legionella

BioRxiv : the Preprint Server for Biology
T. HermannsKay Hofmann
June 2, 2020
Preprint
Open Access

DNA binding reorganizes the intrinsically disordered C-terminal region of PSC in Drosophila PRC1

BioRxiv : the Preprint Server for Biology
J. J. KangNicole Francis
March 30, 2020
Preprint
Open Access

The E3/E4 ubiquitin conjugation factor UBE4B interacts with and ubiquitinates the HTLV-1 Tax oncoprotein to promote NF-kB activation

BioRxiv : the Preprint Server for Biology
Edward William HarhajJiawen Zhang
June 27, 2020
Preprint
Open Access

PCNA-K164 ubiquitination facilitates origin licensing and mitotic DNA synthesis

BioRxiv : the Preprint Server for Biology
W. LeungAnja K Bielinsky
July 2, 2020
Preprint

Targeting the ubiquitin-proteasome system in a pancreatic cancer subtype with hyperactive MYC

BioRxiv : the Preprint Server for Biology
K. LankesMatthias Wirth

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