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Ubiquitin System (Preprints)

Ubiquitin System (Preprints)   diagram by Rogerdodd
Rogerdodd

Ubiquitin is a small regulatory protein that is attached to proteins as a post-translational modification in a process known as ubiquitination to regulate protein turnover, location, or activity. Here is the latest research on the ubiquitin system.

Top 20 most recent papers
bioRxiv

The insulin receptor adaptor IRS2 is an APC/C substrate that promotes cell cycle protein expression and a robust spindle assembly checkpoint

bioRxivNovember 15, 2019
Sandhya ManoharRandall W King
15
bioRxiv

Unmasking functional redundancy of deubiquitylases enables specificity profiling and discovery of novel proteasome substrates

bioRxivNovember 16, 2019
Valentina RossioRandall W King
16
bioRxiv

Discovery of an AKT Degrader with Prolonged Inhibition of Downstream Signaling

bioRxivNovember 20, 2019
Inchul YouAlex Toker
3
bioRxiv

Neuronal Proteostasis is mediated by the switch-like expression of Heme-regulated Kinase 1, acting as both a sensor and effector

bioRxivNovember 7, 2019
Beatriz Alvarez-CastelaoErin Margaret Schuman
10
bioRxiv

Leishmania infection triggers hepcidin-mediated proteasomal degradation of Nramp1 resulting in increased phagolysosomal iron availability

bioRxivOctober 28, 2019
Sourav Banerjee, Rupak Datta
8
bioRxiv

Switch from translation initiation to elongation needs Not4 and Not5 collaboration

bioRxivNovember 22, 2019
George E AllenMartine A Collart
7
bioRxiv

Phosphorylation of the CAMTA3 transcription factor triggers its destabilization and nuclear export.

bioRxivOctober 30, 2019
Xiyuan JiangJustin Lee
8
bioRxiv

Characterization of OTUB1 activation and inhibition by different E2 enzymes

bioRxivNovember 20, 2019
Lauren T QueCynthia P Wolberger
2
bioRxiv

TORC1 regulates vacuole membrane composition through ubiquitin- and ESCRT-dependent microautophagy

bioRxivNovember 26, 2019
X William YangMing Li
15
bioRxiv

SPOP Promotes Ubiquitination and Degradation of MyD88 to Suppress the Innate Immune Response

bioRxivNovember 5, 2019
Gui-Ping ZhaoJie Wen
3
bioRxiv

Transient deSUMOylation of IRF2BP proteins controls early transcription in EGFR signaling

bioRxivOctober 26, 2019
Sina V BaryschFrauke Melchior
2
bioRxiv

Interconversion between Anticipatory and Active GID E3 Ubiquitin Ligase Conformations via Metabolically Driven Substrate Receptor Assembly

bioRxivOctober 31, 2019
Shuai QiaoBrenda A. Schulman
9
bioRxiv

A Small-Molecule Activity-Based Probe for Monitoring Ubiquitin C-terminal Hydrolase L1 (UCHL1) Activity in Live Cells and Zebrafish Embryos

bioRxivNovember 1, 2019
Paul P GeurinkHuib Ovaa
1
bioRxiv

The Pleiades cluster of fungal effector genes inhibit 1 host defenses

bioRxivNovember 1, 2019
Fernando NavarreteArmin Djamei
16
bioRxiv

Genomic Characterization of SiGRFs in Foxtail Millet and SiGRF1-overexpression in Arabidopsis thaliana Promotes Plant Avoidance of Salt Stress

bioRxivNovember 21, 2019
Jia-Ming LiuWei-Jun Zheng
3
bioRxiv

Ubiquitin and SUMO conjugation as biomarkers of Acute Myeloid Leukemias response to chemotherapies

bioRxivOctober 31, 2019
Pierre GatelGuillaume Bossis
5
bioRxiv

Native mass spectrometry can effectively predict PROTAC efficacy

bioRxivNovember 25, 2019
Rebecca BeveridgeTim Clausen
47
1
bioRxiv

N-cadherin SPRY motifs bind unconventionally-secreted Fbxo45 and regulate multipolar neuron migration

bioRxivNovember 1, 2019
Youn NaJonathan A Cooper
3
bioRxiv

Characterization of the Key Region and Phosphorylation Sites of EcaICE1 for its Molecular Interaction with EcaHOS1 Protein from Eucalyptus camaldulensis

bioRxivDecember 2, 2019
Ling ChengYuan-Zhen Lin
2
bioRxiv

Arabidopsis ROOT PHOTOTROPISM2 is a Light-Dependent Dynamic Modulator of Phototropin1

bioRxivDecember 2, 2019
Taro KimuraTatsuya Sakai
4

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