Uracil & Genome Editing

Base editing systems, including those using a uracil DNA glycosylase inhibitor, expand the scope and efficiency of genome editing technologies. The latest research in that area can be found in this feed.

July 31, 2020
Open Access

Ex vivo editing of human hematopoietic stem cells for erythroid expression of therapeutic proteins

Nature Communications
Giulia PavaniMario Amendola
August 5, 2020

CRISPR/Cas: A Successful Tool for Genome Editing in Animal Models

Critical Reviews in Eukaryotic Gene Expression
Bilal AhmedMuhammad Imran Qadir
July 31, 2020
Open Access

Structures of the Cmr-β Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas

Molecular Cell
Nicholas SofosGuillermo Montoya
August 4, 2020
Review
Open Access

Rat models of human diseases and related phenotypes: a systematic inventory of the causative genes

Journal of Biomedical Science
Claude Szpirer
August 6, 2020

Phosphorylation of PLCγ1 by EphA2 receptor tyrosine kinase promotes tumor growth in lung cancer

Molecular Cancer Research : MCR
Wenqiang SongJin Chen
August 4, 2020

Correction of Airway Stem Cells: Genome Editing Approaches for the Treatment of Cystic Fibrosis

Human Gene Therapy
Nicholas E KingBrian R Davis
August 9, 2020
Open Access

Development of a Highly Efficient Multiplex Genome Editing System in Outcrossing Tetraploid Alfalfa (Medicago sativa )

Frontiers in Plant Science
Tezera W WolabuZeng-Yu Wang
August 8, 2020
Open Access

Citrus CsACD2 is a target of Candidatus Liberibacter asiaticus in Huanglongbing disease

Plant Physiology
Zhiqian PangNian Wang
August 2, 2020

Macrophage Lxrα reduces atherosclerosis in Ldlr-/- mice independent of Arl7 transactivation

Biochemical and Biophysical Research Communications
Yongjun YinPeiyang Gao
July 30, 2020
Preprint
Open Access

Base-edited CAR T Cells for combinational therapy against T cell malignancies

BioRxiv : the Preprint Server for Biology
C. GeorgiadisWaseem Qasim
August 2, 2020

A CRISPR first produces squid as clear as glass

Nature
August 8, 2020
Review
Open Access

Genomic, Transcriptomic and Epigenomic Tools to Study the Domestication of Plants and Animals: A Field Guide for Beginners

Frontiers in Genetics
Josué Barrera-RedondoLuis E Eguiarte
August 8, 2020
Review
Open Access

Genetic Engineering Strategies for Euglena gracilis and Its Industrial Contribution to Sustainable Development Goals: A Review

Frontiers in Bioengineering and Biotechnology
Ryo HaradaKengo Suzuki
August 4, 2020

Identification and functional characterisation of late blight resistance polymorphic genes in Russet Burbank potato cultivar

Functional Plant Biology : FPB
Niranjan HegdeAjjamada C Kushalappa
August 5, 2020
Review

CRISPR-Cas9 Genome Editing Tool for the Production of Industrial Biopharmaceuticals

Molecular Biotechnology
Amjad Hayat KhanRahmah Noordin

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