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Von Hippel-Lindau’s Disease

Von Hippel-Lindau’s Disease diagram by Qiao's Pathology
Qiao's Pathology

von Hippel-Lindau syndrome (VHL) is a hereditary condition associated with tumors arising in multiple organs. Tumors in VHL include hemangioblastomas, which are blood vessel tumors of the brain, spinal cord, and eye. Here is the latest research.

Top 20 most recent papers
Indian Journal of Endocrinology and Metabolism

Genetic Profile of Indian Pheochromocytoma and Paraganglioma Patients - A Single Institutional Study

Indian Journal of Endocrinology and MetabolismNovember 20, 2019
Gaurav K AgarwalEesh Bhatia
Angewandte Chemie

Structure-Based Design of a Macrocyclic PROTAC

Angewandte ChemieNovember 19, 2019
Alessio CiulliJane E Wright
Nano Letters

Intratumor Performance and Therapeutic Efficacy of PAMAM Dendrimers Carried by Clustered Nanoparticles

Nano LettersNovember 7, 2019
Hong-Jun LiJun Wang

Hypoxia on vhl-deficient cells to obtain hif related genes through bioinformatics analysis.

bioRxivDecember 3, 2019
Hua Lin, Hong-wei Liu
Molecular Cancer Therapeutics

Mutations and Response to Rapalogs in Patients with Metastatic Renal Cell Carcinoma

Molecular Cancer TherapeuticsOctober 25, 2019
Amin H NassarDavid J. Kwiatkowski

Mutational profile and genotype/phenotype correlation of non-familial pheochromocytoma and paraganglioma

OncotargetOctober 15, 2019
Shatha AlbattalAli Matar Alzahrani
Journal of Medicinal Chemistry

Discovery of Highly Potent and Efficient PROTAC Degraders of Androgen Receptor (AR) by Employing Weak Binding Affinity VHL E3 Ligase Ligands

Journal of Medicinal ChemistryDecember 5, 2019
Xin HanShaomeng J Wang

A novel strategy to block mitotic progression for targeted therapy

EBioMedicineOctober 25, 2019
Junlong Jack ChiYong Wan
Journal of Hypertension

Concurrent heterozygous Von-Hippel-Lindau and transmembrane-protein-127 gene mutation causing an erythropoietin-secreting pheochromocytoma in a normotensive patient with severe erythrocytosis

Journal of HypertensionSeptember 19, 2019
Aurelio NegroAderville Cabassi
Science Signaling

HIF-independent synthetic lethality between CDK4/6 inhibition and VHL loss across species

Science SignalingOctober 1, 2019
Hilary E NicholsonWilliam G. Kaelin
Langmuir : the ACS Journal of Surfaces and Colloids

Location of the Positive Charges in Cationic Amphiphiles Modulates Their Mechanism of Action against Model Membranes

Langmuir : the ACS Journal of Surfaces and ColloidsOctober 8, 2019
Marcio M AlmeidaKarin A Riske
Clinical Neurology and Neurosurgery

Central nervous system hemangioblastomas in the elderly (over 65 years): Clinical characteristics and outcome analysis

Clinical Neurology and NeurosurgeryNovember 25, 2019
Qiguang WangXu-hui Hui

Stabilization of myeloid-derived HIFs promotes vascular regeneration in retinal ischemia

AngiogenesisOctober 3, 2019
Pilar VillacampaJames W B Bainbridge
Orphanet Journal of Rare Diseases

Growth characteristics and therapeutic decision markers in von Hippel-Lindau disease patients with renal cell carcinoma

Orphanet Journal of Rare DiseasesOctober 28, 2019
Patrick SchuhmacherStefan Zschiedrich
JCI Insight

Rb1/Rbl1/Vhl loss induces mouse subretinal angiomatous proliferation and hemangioblastoma

JCI InsightOctober 16, 2019
Ran WeiDanian Chen
International Journal of Biological Macromolecules

Structure of maltotetraose-forming amylase from Pseudomonas saccharophila STB07 provides insights into its product specificity

International Journal of Biological MacromoleculesNovember 18, 2019
Ziqian ZhangZhao-Feng Li

The cause of melena in a female with Von Hippel-Lindau disease

GastroenterologySeptember 24, 2019
Peace EnehConor G Loftus
Frontiers in Oncology

Hemangioblastoma Instead of Renal Cell Carcinoma Plays a Major Role in the Unfavorable Overall Survival of Von Hippel-Lindau Disease Patients

Frontiers in OncologyOctober 9, 2019
Bo-Wen ZhouKan Gong
World Journal of Surgery

Clinical and Biochemical Features of Pheochromocytoma Characteristic of Von Hippel-Lindau Syndrome

World Journal of SurgeryNovember 26, 2019
Shimena R LiLinwah Yip
Frontiers in Genetics

Frequent Mutations of VHL Gene and the Clinical Phenotypes in the Largest Chinese Cohort With Von Hippel-Lindau Disease

Frontiers in GeneticsSeptember 18, 2019
Bao-An HongKan Gong

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