X-linked severe combined immunodeficiency is caused by mutations in the common cytokine-receptor gamma chain, resulting in disruption of development of T lymphocytes and natural-killer cells. Here is the latest research.
HIV infection increases the risk of non-communicable diseases common in the aged, including cardiovascular disease, neurocognitive decline, non-aids malignancies, osteoporosis, and frailty. Discover the latest research in AIDS malignancies.
Ataxia telangiectasia is a rare neurodegenerative diseases caused by defects in the ATM gene, which is involved in DNA damage recognition and repair pathways. Here is the latest research on this autosomal recessive disease.
Chronic Granulomatous Disease is an inherited immunodeficiency disorder that is characterized by recurrent infections and granuloma formation. Discover the latest research on Chronic Granulomatous Disease here.
Common variable immunodeficiency is a primary immunodeficiency disease characterized by hypogammaglobulinemia and lack of antibody production. Here is the latest research.
Deltaretroviruses such as human T-lymphotropic virus type 1 and bovine leukemia virus induce a persistent infection that remains generally asymptomatic but can also lead to leukemia or lymphoma. Here is the latest research on Deltaretroviruses infections.
HIV/AIDS is a global pandemic with Sub-Saharan Africa being the most affected region. In 2017, almost 37 million people were infected with HIV and almost 1 million deaths occurred due to AIDS. Find the latest research on HIV/AIDS here.
HIV co-infection worsens the histological course of other viral infections, such as HCV by increasing and accelerating the risk of cirrhosis or leading to rare but lethal fibrosing cholestatic hepatitis. Discover the latest research on HIV co-infection.
While good nutrition is important for all individuals, it is especially an important issue for those infected HIV for several reasons. HIV infection impacts metabolic, cardiovascular, and psychological functioning and nutrition is key in managing these changes. Find the latest research on HIV and nutrition here.
The development to make HIV vaccines for both the prevention and treatment of HIV infection is ongoing. Some individuals with HIV infection produce antibodies which suppress the virus and allow the patients to remain asymptomatic, suggesting that a vaccine may be achievable. Find the latest research on HIV vaccines here.
HIV-1 reverse transcriptase is among the earliest HIV proteins identified and is involved in viral replication. More than half of investigational long-acting antivirals target hiv-1 reverse transcriptase and/or integrase (hiv-1 in). Discover the latest research here.