Zinc Finger Nucleases

Zinc-finger nucleases are engineered restriction enzymes that enable gene editing by targeting specific DNA sequences in the genome. Here is the latest research.

January 21, 2022

H and HL synergistically regulate jasmonate-triggered trichome formation in tomato.

Horticulture Research
Bing HuaShuang Wu
January 21, 2022

Synthetic multistability in mammalian cells.

Ronghui ZhuMichael B Elowitz
January 20, 2022
Open Access

Genetic control of KRAB-ZFP genes explains distal CpG-site methylation which associates with human disease phenotypes.

BioRxiv : the Preprint Server for Biology
Andrew D BretherickC. P. Ponting
January 20, 2022
Open Access

KRAB zinc finger protein ZNF676 controls the transcriptional influence of LTR12-related endogenous retrovirus sequences.

Mobile DNA
Alexandra IouranovaDidier Trono
January 20, 2022

Nuclear and mitochondrial DNA editing in human cells with zinc finger deaminases.

Nature Communications
Kayeong LimJin-Soo Kim
January 20, 2022

Mutation in senataxin alters the mechanism of R-loop resolution in amyotrophic lateral sclerosis 4.

Brain : a Journal of Neurology
Annapoorna KannanLaxman Gangwani
January 19, 2022

Reducing HIV-1 env gene CpG frequency increases the replication capacity of the HXB2 virus strain.

Virus Research
Ana Jordan-PaizMiguel Angel Martinez
January 19, 2022

GATA3 positivity is associated with poor prognosis in patients with oesophageal squamous cell carcinoma.

Journal of Clinical Pathology
Zhikai ChiLan Peng
January 19, 2022

2‑Cl‑IB‑MECA regulates the proliferative and drug resistance pathways, and facilitates chemosensitivity in pancreatic and liver cancer cell lines.

International Journal of Molecular Medicine
Jana KotulovaPetr Dzubak
January 19, 2022

Structures of Silver Fingers and a Pathway to Their Genotoxicity.

Angewandte Chemie
Katarzyna KluskaArtur Krezel
January 17, 2022

ZFP207 sustains pluripotency by coordinating OCT4 stability, alternative splicing and RNA export.

EMBO Reports
Sandhya MallaFrancesca Aguilo
January 17, 2022

A novel HD-Zip I/C2H2-ZFP/WD-repeat complex regulates the size of spine base in cucumber.

The New Phytologist
Sen YangLuming Yang
January 17, 2022

Structural and biochemical characterization of human Schlafen 5.

Nucleic Acids Research
Felix J MetznerKatja Lammens
January 17, 2022

Meta-QTLs, ortho-MQTLs and candidate genes for the traits contributing to salinity stress tolerance in common wheat (Triticum aestivum L.).

Physiology and Molecular Biology of Plants : an International Journal of Functional Plant Biology
Neeraj PalSundip Kumar
January 17, 2022
Open Access

The functions and prognostic value of Krüppel-like factors in breast cancer.

Cancer Cell International
Ke-Yun ZhuYue Yu

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