β-Alanine supplementation increased physical performance and improved executive function following endurance exercise in middle aged individuals

Journal of the International Society of Sports Nutrition
Taylor FurstPeter J Horvath

Abstract

Sarcopenia, a reduction in muscle mass and function seen in aging populations, may be countered by improving systemic carnosine stores via beta-Alanine (β-alanine) supplementation. Increasing systemic carnosine levels may result in enhanced anti-oxidant, neuro-protective and pH buffering capabilities. This enhancement should result in improved exercise capacity and executive function. Twelve healthy adults (average age = 60.5 ± 8.6 yrs, weight = 81.5 ± 12.6 kg) were randomized and given either 2.4 g/d of β-alanine (BA) or Placebo (PL) for 28 days. Exercise capacity was tested via bouts on a cycle ergometer at 70% VO2 peak. Executive function was measured by Stroop Tests 5 min before exercise (T1), immediately before exercise (T2), immediately following fatigue (T3), and 5 min after fatigue (T4). Lactate measures were taken pre/post exercise. Heart rate, Rating of Perceived Exertion (RPE) and VO2 were recorded throughout exercise testing. PRE average time-to-exhaustion (TTE) for the PL and BA group were not significantly different (Mean ± SD; 9.4 ± 1.4mins vs 11.1 ± 2.4mins, respectively, P = 0.7). POST BA supplemented subjects cycled significantly longer than PRE (14.6 ± 3.8mins vs 11.1 ± 2.4mins, respectively, P = 0.04) while ...Continue Reading

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Citations

Apr 14, 2019·Advances in Nutrition·Eimear DolanBruno Gualano
Jan 23, 2020·Nutrients·Yasutomi KameiShinji Miura
Mar 9, 2019·Recent Patents on Drug Delivery & Formulation·Sergei V Jargin
Sep 19, 2020·Journal of Strength and Conditioning Research·Adam J WellsJay R Hoffman
Nov 20, 2019·Bioorganic & Medicinal Chemistry·Ekaterina S KropotovaMark I Mosevitsky
Mar 4, 2021·Nutrients·Christianto PutraKelsey M Mangano
Oct 27, 2020·Journal of Strength and Conditioning Research·Adam J WellsJay R Hoffman
Mar 24, 2020·Chemical Research in Toxicology·Klaudia ChmielewskaMaja Przybyłowska

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