Abstract
The dissemination of Enterobacteriaceae expressing resistance to clinically important antibiotics such as extended-spectrum cephalosporins (ESC), carbapenems, and fluoroquinolones is of critical concern to both human and veterinary medicine. In healthcare facilities, the movement of patients, personnel, and equipment provides an opportunity for Enterobacteriaceae carrying antibiotic resistance genes to disseminate in the hospital environment where they pose a threat to patients, staff, and hospital visitors. We collected environmental samples using electrostatic cloths to estimate the frequency of resistant Enterobacteriaceae contamination on human and veterinary hospital surfaces. Samples were enriched in nutrient broth modified with antibiotics to provide specific selection pressure to select for bacteria expressing AmpC β-lactamase (blaCMY), extended-spectrum β-lactamase (ESBL, blaCTX-M), carbapenemase, quinolone, and fluoroquinolone-resistant phenotypes. A total of 31 contact surfaces were sampled at each of five visits to two human hospitals. In addition, 34 surfaces were sampled at each of three visits to a veterinary hospital serving both farm animal and companion animal patients. Isolates expressing the blaCMY phenotype...Continue Reading
References
Sep 15, 2001·Antimicrobial Agents and Chemotherapy·P L WinokurG V Doern
May 3, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Mary K HaydenRobert A Weinstein
Oct 13, 2006·Archives of Internal Medicine·Susan S HuangRichard Platt
May 19, 2010·Antimicrobial Agents and Chemotherapy·Alexandra O'KeefeShelley C Rankin
Aug 17, 2010·Foodborne Pathogens and Disease·Thomas E WittumWondwossen A Gebreyes
Nov 9, 2010·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·S NseirA Durocher
Dec 16, 2010·Epidemiology and Infection·J S GibsonD J Trott
Mar 30, 2011·Antimicrobial Agents and Chemotherapy·Gisele PeiranoJohann D D Pitout
Jun 15, 2011·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Jonathan A OtterGary L French
Sep 29, 2011·Antimicrobial Agents and Chemotherapy·Bashar W ShaheenDawn M Boothe
Sep 14, 2012·Infection·E MeyerF Schwab
Mar 12, 2013·Vector Borne and Zoonotic Diseases·Joany van BalenArmando E Hoet
Apr 11, 2013·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·David J Weber, William A Rutala
Apr 17, 2013·Antimicrobial Agents and Chemotherapy·Bashar W ShaheenDawn M Boothe
Apr 20, 2013·ELife·Se Jin SongRob Knight
Sep 21, 2013·Journal of the American Veterinary Medical Association·Elizabeth HamiltonJohn B Kaneene
May 21, 2014·Trends in Microbiology·Liam S RedgraveLaura J V Piddock
May 30, 2014·Scientific Reports·Neena KanwarPatrick Boerlin
Jun 24, 2015·Antimicrobial Agents and Chemotherapy·Dixie F MollenkopfThomas E Wittum
Jan 5, 2018·MMWR. Morbidity and Mortality Weekly Report·Sae-Rom ChaeAlexander Kallen
Citations
Jul 2, 2020·Transactions of the Royal Society of Tropical Medicine and Hygiene·Robab AzargunShirin Eyvazi
Jun 25, 2020·Antimicrobial Resistance and Infection Control·Janne S SchmidtBarbara Willi
Jan 7, 2021·Journal of the American Veterinary Medical Association·Emily E FeyesThomas E Wittum
Jun 26, 2020·Antimicrobial Resistance and Infection Control·Janne S SchmidtBarbara Willi