PMID: 9544333Apr 17, 1998Paper

0.9% sodium chloride injection with and without heparin for maintaining peripheral indwelling intermittent-infusion devices in infants

American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists
T J Nelson, S M Graves

Abstract

The use of 0.9% sodium chloride injection with and without heparin sodium for maintaining peripheral indwelling intermittent-infusion devices (PIIIDs) in infants was studied. In this double-blind study, children up to one year of age who had a 24-gauge PIIID through which a continuous i.v. infusion was no longer running were randomly assigned to have their PIIID capped with 0.9% sodium chloride injection with or without heparin sodium 10 units/mL. PIIIDs were capped every eight hours if no medications were administered; otherwise, they were capped after each dose of an i.v. drug. The heparin group had 26 patients with 28 evaluable PIIIDs, and the 0.9% sodium chloride injection group had 32 patients with 46 evaluable PIIIDs. The two groups did not differ significantly in variables assessing the duration of PIIID use, reasons for removal of PIIIDs, mean number of cappings, irritant potential of administered drugs, or severity of medication-related irritation. There was no significant difference between 0.9% sodium chloride injection with and without heparin sodium 10 units/mL in maintaining 24-gauge PIIIDs in children younger than one year.

Citations

Oct 20, 2005·The Cochrane Database of Systematic Reviews·P S ShahA K Sinha
Jun 23, 2006·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·UNKNOWN ASHP Commission on Therapeutics
Jan 25, 2007·International Journal of Nursing Practice·Esther MokMoon Fai Chan
Aug 16, 2017·Experimental and Therapeutic Medicine·Tao YouYang Jiao
Apr 16, 2002·Neonatal Network : NN·K S HanrahanS Berends
Jul 7, 2011·Advances in Neonatal Care : Official Journal of the National Association of Neonatal Nurses·Linda CookRegina M Cusson

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