1-Aminocyclopropane-1-Carboxylic Acid Oxidase (ACO): The Enzyme That Makes the Plant Hormone Ethylene

Frontiers in Plant Science
Maarten Houben, Bram Van de Poel

Abstract

The volatile plant hormone ethylene regulates many plant developmental processes and stress responses. It is therefore crucial that plants can precisely control their ethylene production levels in space and time. The ethylene biosynthesis pathway consists of two dedicated steps. In a first reaction, S-adenosyl-L-methionine (SAM) is converted into 1-aminocyclopropane-1-carboxylic acid (ACC) by ACC-synthase (ACS). In a second reaction, ACC is converted into ethylene by ACC-oxidase (ACO). Initially, it was postulated that ACS is the rate-limiting enzyme of this pathway, directing many studies to unravel the regulation of ACS protein activity, and stability. However, an increasing amount of evidence has been gathered over the years, which shows that ACO is the rate-limiting step in ethylene production during certain dedicated processes. This implies that also the ACO protein family is subjected to a stringent regulation. In this review, we give an overview about the state-of-the-art regarding ACO evolution, functionality and regulation, with an emphasis on the transcriptional, post-transcriptional, and post-translational control. We also highlight the importance of ACO being a prime target for genetic engineering and precision bree...Continue Reading

References

Aug 15, 1991·Proceedings of the National Academy of Sciences of the United States of America·A J HamiltonD Grierson
Dec 23, 1987·Nucleic Acids Research·M J HoldsworthD Grierson
Apr 1, 1996·The Plant Journal : for Cell and Molecular Biology·C S BarryD Grierson
Jan 13, 2000·Molecular Biotechnology·A Aitken
Jun 1, 2002·Plant & Cell Physiology·Mei-Chu ChungShang Fa Yang
Sep 27, 2002·Journal of Experimental Botany·Lucille Alexander, Don Grierson
Apr 26, 2003·The Plant Journal : for Cell and Molecular Biology·Sara Andersson-GunneråsBjörn Sundberg
Sep 16, 2003·Plant Physiology·Filip VandenbusscheDominique Van Der Straeten
May 28, 1965·Science·S P BURG, E A BURG
Nov 3, 2004·Transgenic Research·Abhaya M DandekariDavid J James
Feb 11, 2005·The Plant Journal : for Cell and Molecular Biology·Kazumi NakabayashiEiji Nambara
Apr 5, 2005·Nature Genetics·Markus SchmidJan U Lohmann
May 12, 2005·Journal of the American Chemical Society·David L TierneyBrian M Hoffman
Jul 26, 2005·DNA Sequence : the Journal of DNA Sequencing and Mapping·Simone Sell, Reinhard Hehl
Aug 2, 2005·Plant Physiology·David P DixonRobert Edwards
Jan 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·D O Adams, S F Yang
May 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·G D PeiserC T Walsh
Mar 1, 1966·Plant Physiology·M Lieberman, A Kunishi
Sep 1, 1989·Plant Physiology·H Kende
Nov 3, 2007·Science·Siobhan M BradyPhilip N Benfey
Apr 10, 2008·The Plant Journal : for Cell and Molecular Biology·Zhefeng LinDon Grierson
Jul 10, 2008·Transgenic Research·Rodolfo López-GómezLuis Herrera-Estrella
Mar 19, 2009·Proceedings of the National Academy of Sciences of the United States of America·Jonathan LoveBjörn Sundberg

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Citations

Jan 11, 2020·Frontiers in Plant Science·Juan SuarezÜner Kolukisaoglu
Jan 11, 2020·Frontiers in Plant Science·Joanna K Polko, Joseph J Kieber
Aug 25, 2020·Plant Signaling & Behavior·Han Yong Lee, Gyeong Mee Yoon
Aug 6, 2020·International Journal of Molecular Sciences·Üner Kolukisaoglu
Dec 19, 2019·Nature Communications·Kenward VongKatsunori Tanaka
Jul 3, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Johan J P BaarsArend van van Peer
Aug 14, 2020·The New Phytologist·Jolien PattynBram Van de Poel
Jan 16, 2021·Journal of Proteomics·Janet Juarez-EscobarEliel Ruíz-May
Nov 17, 2020·Journal of Plant Physiology·Tiantian XiongXiaoyang Zhu
Jan 21, 2021·International Journal of Molecular Sciences·Yogesh Ahlawat, Tie Liu
Oct 30, 2020·Science Advances·Songkui CuiSatoko Yoshida
Nov 7, 2020·Journal of Hazardous Materials·Javaid Akhter BhatFrancisco J Corpas
Feb 3, 2021·International Journal of Molecular Sciences·Dong XuRenying Zhuo
Oct 15, 2020·International Journal of Molecular Sciences·Cíntia H D SagawaAbhaya M Dandekar
Jun 3, 2021·International Journal of Molecular Sciences·Carlos Lopez-OrtizUmesh K Reddy
Jul 3, 2021·International Journal of Molecular Sciences·Md Mahadi HasanXiang-Wen Fang
Jul 16, 2021·Frontiers in Plant Science·Riyazuddin Riyazuddin, Ravi Gupta
Aug 10, 2021·Journal of Experimental Botany·Gwilherm BrisouAbdelhafid Bendahmane
Aug 22, 2021·Trends in Plant Science·Vipul MishraVijay Pratap Singh
Feb 27, 2020·Journal of Agricultural and Food Chemistry·Ying-Ying WuXue-Ren Yin
Sep 21, 2021·Frontiers in Plant Science·Qingfei LiXinzheng Li

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Methods Mentioned

BETA
one-hybrid
glycosylation
pull-down
two-hybrid
transgenic

Software Mentioned

Phytozome
BLASTp
MUSCLE
RAxML
Geneious

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