1-N-Acetylspermidine: occurrence in normal human serum

Biomedical Mass Spectrometry
R G SmithG D Daves


Using gas chromatography mass spectrometry following derivatization (N-trifluoroacetylation), 1-N-acetylspermidine was found to occur in normal human serum at a level of approximately 0.008--0.5 nmol ml(-1), i.e. about two orders of magnitude lower than the corresponding spermidine level. No evidence for the occurrence in serum of the isomeric 8-N-acetylspermidine was found. Mass spectra of authentic samples of trifluoroactylated 1-N- and 8-N-acetylspermidine are presented.


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Related Concepts

Chromatography, Gas-Liquid
Mass Spectrometry

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