1-Year Outcomes After Edge-to-Edge Valve Repair for Symptomatic Tricuspid Regurgitation: Results From the TriValve Registry

JACC. Cardiovascular Interventions
Michael MehrJörg Hausleiter

Abstract

The purpose of this study was to evaluate procedural and 1-year clinical and echocardiographic outcomes of patients treated with tricuspid edge-to-edge repair. Transcatheter edge-to-edge repair has been successfully performed in selected patients with symptomatic tricuspid regurgitation (TR) and high risk for surgery, but outcome data are sparse. This analysis of the multicenter international TriValve (Transcatheter Tricuspid Valve Therapies) registry included 249 patients with severe TR treated with edge-to-edge repair in compassionate and/or off-label use. Clinical and echocardiographic outcomes were prospectively collected and retrospectively analyzed. In 249 patients (mean age 77 ± 9 years; European System for Cardiac Operative Risk Evaluation II score 6.4% [interquartile range: 3.9% to 13.9%]), a successful procedure with TR reduction to grade ≤2+ was achieved in 77% by placement of 2 ± 1 tricuspid clips. Concomitant treatment of severe TR and mitral regurgitation was performed in 52% of patients. At 1-year follow-up, significant and durable improvements in TR severity (TR ≤2+ in 72% of patients) and New York Heart Association functional class (≤II in 69% of patients) were observed. All-cause mortality was 20%, and the com...Continue Reading

Citations

Mar 11, 2020·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Mizuki MiuraFrancesco Maisano
Apr 7, 2020·Expert Review of Cardiovascular Therapy·Vinayak NagarajaAmar Krishnaswamy
Feb 20, 2020·Journal of Cardiovascular Medicine·Marco RussoMartin Andreas
May 21, 2020·Frontiers in Cardiovascular Medicine·Mirjam G WinkelFabien Praz
Jun 6, 2020·Frontiers in Cardiovascular Medicine·Mirjam Gauri WinkelPeter Wenaweser
Sep 10, 2020·Frontiers in Cardiovascular Medicine·Guillem Muntané-CarolJosep Rodés-Cabau
Aug 29, 2020·Journal of Cardiovascular Medicine·Gregorio ZacconeMarianna Adamo
Dec 10, 2020·Praxis·Mirjam WinkelFabien Praz
Jan 6, 2021·Journal of the American Heart Association·Akram KawsaraMohamad Alkhouli
Nov 16, 2020·JACC. Cardiovascular Interventions·Neil P Fam, Geraldine Ong
Jan 26, 2021·The Canadian Journal of Cardiology·Guillem Muntané-CarolJosep Rodés-Cabau
Dec 11, 2020·International Journal of Cardiology·Faeez M AliNeil P Fam
Jan 23, 2021·Journal of the American College of Cardiology·Philipp LurzUNKNOWN TRILUMINATE Investigators
Nov 12, 2020·Frontiers in Cardiovascular Medicine·Antonio MangieriAzeem Latib
Mar 7, 2020·The Annals of Thoracic Surgery·Davide CarinoMichele De Bonis
Mar 6, 2021·JACC. Cardiovascular Interventions·Claudio MontaltoAntonio Mangieri
Feb 23, 2021·The Canadian Journal of Cardiology·Guillem Muntané-CarolJosep Rodés-Cabau
Jan 20, 2020·JACC. Cardiovascular Interventions·Michael MehrUNKNOWN TriValve and TRAMI Investigators
Mar 24, 2021·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Niklas F BoederHolger M Nef
May 4, 2021·Current Opinion in Organ Transplantation·Anandbir S BathRami N Khouzam
Mar 17, 2020·JACC. Cardiovascular Interventions·Neil P FamMark D Peterson
May 4, 2020·JACC. Cardiovascular Interventions·David W M Muller
May 10, 2021·The Canadian Journal of Cardiology·Nir LeviDavid Meerkin
May 20, 2021·Current Opinion in Organ Transplantation·Anandbir S BathRami N Khouzam
May 24, 2021·Cardiovascular Revascularization Medicine : Including Molecular Interventions·Fahad AlqahtaniMohamad Alkhouli
Jun 12, 2021·JACC. Cardiovascular Interventions·Tobias Friedrich RufRalph Stephan von Bardeleben
Jan 13, 2021·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Neil P FamGeraldine Ong
Aug 8, 2021·Heart·Johanna VogelhuberGeorg Nickenig
Aug 17, 2021·Current Opinion in Cardiology·Tanush GuptaSachin S Goel
Aug 21, 2021·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·F MeijerinkJ Baan
Aug 28, 2021·The Journal of Thoracic and Cardiovascular Surgery·Tom Kai Ming WangMilind Y Desai
Aug 16, 2021·European Journal of Heart Failure·Marco Guazzi, Marianna Adamo

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