10-Hydroxycamptothecin produced by a new endophytic Xylaria sp., M20, from Camptotheca acuminata

Biotechnology Letters
Kaihui LiuWenqiang Chen

Abstract

A new 10-hydroxycamptothecin (HCPT)-producing fungus was isolated from Camptotheca acuminata. The strain was classified as a Xylaria sp. based on the internal transcribed spacer and 18S rDNA gene analysis. All elicitors tested, except methyl jasmonate, increased HCPT production in submerged culture. The maximum yield was 5.4 mg HCPT/l(-1), when salicylic acid was added at 0.1 mM to the culture medium.

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Jun 2, 2009·Journal of Industrial Microbiology & Biotechnology·Kaihui LiuWenqiang Chen

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Citations

Aug 1, 2015·Biotechnology Advances·Aarthi Venugopalan, Smita Srivastava
Feb 26, 2011·Biotechnology Research International·Mariana Recco PimentelGláucia Maria Pastore
May 16, 2014·Chemistry & Biodiversity·Fei SongTang Wang
Aug 4, 2020·Archives of Microbiology·Matheus Henrique Reis da SilvaDerlene Attili de Angelis
Mar 17, 2021·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Qingyan RuanGuoyin Kai

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