1.0 T open-configuration magnetic resonance-guided microwave ablation of pig livers in real time

Scientific Reports
Jun DongPeihong Wu

Abstract

The current fastest frame rate of each single image slice in MR-guided ablation is 1.3 seconds, which means delayed imaging for human at an average reaction time: 0.33 seconds. The delayed imaging greatly limits the accuracy of puncture and ablation, and results in puncture injury or incomplete ablation. To overcome delayed imaging and obtain real-time imaging, the study was performed using a 1.0-T whole-body open configuration MR scanner in the livers of 10 Wuzhishan pigs. A respiratory-triggered liver matrix array was explored to guide and monitor microwave ablation in real-time. We successfully performed the entire ablation procedure under MR real-time guidance at 0.202 s, the fastest frame rate for each single image slice. The puncture time ranged from 23 min to 3 min. For the pigs, the mean puncture time was shorted to 4.75 minutes and the mean ablation time was 11.25 minutes at power 70 W. The mean length and widths were 4.62 ± 0.24 cm and 2.64 ± 0.13 cm, respectively. No complications or ablation related deaths during or after ablation were observed. In the current study, MR is able to guide microwave ablation like ultrasound in real-time guidance showing great potential for the treatment of liver tumors.

References

Nov 2, 2002·Journal of Magnetic Resonance Imaging : JMRI·Shigehiro MorikawaMasaki Fujimura
Jan 20, 2005·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Hajime AbeTohru Tani
Jan 26, 2008·Journal of Magnetic Resonance Imaging : JMRI·Stephan Clasen, Philippe L Pereira
Mar 23, 2011·Cognition·Don van RavenzwaaijEric-Jan Wagenmakers
Aug 27, 2014·Journal of Vascular and Interventional Radiology : JVIR·Meghan G LubnerChristopher L Brace

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Citations

Jul 21, 2016·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Benjamin KaltenbachStephan Zangos
Apr 22, 2016·World Journal of Gastroenterology : WJG·Robert M Eisele

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X-ray

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SPSS
Statistical Package for the Social Science ( SPSS

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