10-year trends in statin utilization in Taiwan: a retrospective study using Taiwan's National Health Insurance Research Database

BMJ Open
Hsing-Chun HsiehChristine Y Lu

Abstract

Statins have been commonly used to treat patients with hypercholesterolaemia and to prevent cardiovascular disease (CVD) worldwide. This study examined trends in use of statins in Taiwan from 2002 to 2011. This is a retrospective observational study focusing on the utilisation of statins. The monthly claims data for statins between 2002 and 2011 were retrieved from Taiwan's National Health Insurance Research Database. We calculated the yearly prescription rate per new user for each statin. Products were classified as high-intensity/moderate-intensity/low-intensity statins by type of statin and dosage. Users were also classified based on disease histories. The number of statin users increased from 10 299 (~1.4% of adults) in 2002 to 50 687 (~6.3% of adults) in 2011. Atorvastatin was the most commonly used agent (28.4%-36.7%) during the study period. After 2007, simvastatin ranked second with 21.7% market share, followed by rosuvastatin, a newer agent that exhibited a substantial growth in prescription rates (3.4% in 2005 and 19.5% in 2011). In 2011, 94.0% of new statin users used statin monotherapies, and 6.0% used combination therapies. Use of moderate-intensity statins increased from 49.0% in 2002 to 71.0% in 2011, while high-...Continue Reading

Citations

Nov 28, 2018·Current Medical Research and Opinion·Jun-Jun YehChia-Hung Kao
Mar 6, 2018·Journal of Public Health·Feng-Jen Tsai, Valérie Junod
Dec 21, 2019·Biomédica : revista del Instituto Nacional de Salud·Andres Gaviria-MendozaJorge E Machado-Alba
Sep 18, 2020·American Journal of Men's Health·H M WangT T Guo
May 24, 2018·Cardiovascular Drugs and Therapy·Richard Ofori-AsensoDanny Liew
Aug 7, 2020·Journal of Primary Care & Community Health·Andrés Gaviria-MendozaJorge Enrique Machado-Alba
Jun 7, 2021·Atherosclerosis·Joseph E BlaisEsther W Chan

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