11-Mercaptoundecanoic acid capped gold nanoclusters with unusual aggregation-enhanced emission for selective fluorometric hydrogen sulfide determination

Mikrochimica Acta
Fengniu LuHengdao Quan

Abstract

In present study, we discovered unusual solvent-mediated aggregation-enhanced emission (AEE) character of 11-mercaptoundecanoic acid capped gold nanoclusters (MUA-Au NCs). When aggregated in aqueous media, the MUA-Au NCs showed strong emission, which was weakened by adding ethanol. Interestingly, the suppressed emission was selectively enhanced in the presence of hydrogen sulfide (H2S) because H2S was absorbed onto Au NCs through the strong sulfur-gold bonding affinity. The hydrolyzed H2S, namely, HS-, made the Au NCs negatively charged, which aggregated again due to decreased solubility. The H2S-mediated fluorescence enhancement can be further amplified by introducing a hydrophilic thiolate (glutathione, GSH) onto the surface of Au NCs (GSH/MUA-Au NCs), which enabled sensitive determination of H2S. Under the optimized condition, a detection limit of 35 nM was achieved. The determination was not interfered by other anions such as F-, Cl-, Br-, I-, OAc-, N3-, NO3-, HCO3-, SCN-, SO32-, and SO42-. This excellent sensing performance allowed practical application of the GSH/MUA-Au NC-based sensing platform to accurate determination of H2S in human serum samples. Graphical abstractUnusual aggregation-enhanced emission character of 11...Continue Reading

References

Sep 21, 2002·Chemical Communications : Chem Comm·J LuoB Z Tang
Aug 4, 2007·Angewandte Chemie·Chih-Ching HuangHuan-Tsung Chang
Aug 20, 2009·Chemical Society Reviews·Meaghan E Germain, Michael J Knapp
Oct 1, 2011·Chemical Communications : Chem Comm·Zhiqin YuanEdward S Yeung
Oct 3, 2014·Analytical Chemistry·Li-Yi ChenHuan-Tsung Chang
Apr 1, 2015·Analytical Chemistry·Zhiqin YuanEdward S Yeung
Jun 11, 2015·Journal of the American Chemical Society·Kyunglim PyoDongil Lee
Sep 25, 2015·Chemical Society Reviews·Yu TaoXiaogang Qu
Oct 23, 2015·Chemical Reviews·Ju MeiBen Zhong Tang
Aug 6, 2016·Science·Beatriz Santiago-GonzalezSergio Brovelli
Feb 3, 2018·Chemistry : a European Journal·Shan JinManzhou Zhu
Apr 25, 2019·ACS Applied Materials & Interfaces·Yiyuan B YinMichael S Wong

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Citations

Jan 24, 2021·Analytical and Bioanalytical Chemistry·Shemsu Ligani FerejaWei Chen
Mar 12, 2021·Toxicology in Vitro : an International Journal Published in Association with BIBRA·Monika KvakovaMarian Antalik
Nov 6, 2021·Langmuir : the ACS Journal of Surfaces and Colloids·Maryam Alyari, Robert W J Scott

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