PMID: 16538001Mar 16, 2006Paper

123I-metaiodo-benzylguanidine myocardial scintigraphy in the Brugada-type ECG

The Journal of Medical Investigation : JMI
Takashi KawaguchiSusumu Ito

Abstract

The degree of ST-segment elevation and amplitude of J waves, which may change in patients with the Brugada-type electrocardiogram (ECG) over time, are influenced by autonomic nervous activity and the administration of antiarrhythmic drugs. In the present study, we evaluated whether the shape of ST-segment elevation in patients with a Brugada-type ECG might alter the parameters of an 123I-MIBG myocardial scintigraphy and body surface signal-averaged ECG (SAECG). The subjects consisted of 12 patients with a Brugada-type ECG and 15 healthy volunteers (N group). The patients with a Brugada-type ECG were classified into the following 2 groups based on the type of ST-segment elevation: 6 patients with the coved type ST-segment elevation (C group), and 6 patients with the saddle-back type ST-segment elevation (S group). Planar and SPECT images were obtained 15 minutes (early images) and 3 hours (delayed images) after the administration of 123I-MIBG, respectively. In addition, the washout rate (% WR) of 123I-MIBG was obtained in a bull's eye map of the SPECT image. There were no significant differences in the early H/M ratio between the C and S groups. In the C group, however, there were some patients who showed a decreased accumulatio...Continue Reading

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Citations

Dec 6, 2007·Circulation Journal : Official Journal of the Japanese Circulation Society·Masayasu Hiraoka
Sep 29, 2007·Journal of Cardiovascular Electrophysiology·Mitsuhiro NishizakiMasayasu Hiraoka
Feb 6, 2010·Journal of Cardiovascular Electrophysiology·Anna KostopoulouDennis Cokkinos
Aug 28, 2021·Nutrients·Sara D'ImperioCarlo Pappone

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