125I reimplantation in patients with poor initial dosimetry after prostate brachytherapy

International Journal of Radiation Oncology, Biology, Physics
Mira KeyesW James Morris

Abstract

In this case report, we describe 7 patients with suboptimal dosimetry after (125)I prostate brachytherapy who underwent a second implant procedure to improve the dosimetric coverage of the prostate. Seven patients underwent second (125)I implants for suboptimal dosimetry after their initial implant for prostate cancer. The pretreatment characteristics (clinical stage, Gleason score, initial prostate-specific antigen level, location of positive cores, International Prostate Symptom Score, potency, use of androgen suppression, initial implant planning characteristics) were noted. The "Day 30" CT-based dosimetry parameters after the first implant and "Day 0" CT-based dosimetry after the reimplant were recorded (volumes of prostate and rectum covered by 100% and 150% of the dose and dose covering 90% of the prostate volume). The toxicity of the second procedure, International Prostate Symptom Scores before and after reimplantation, the clinical course, and prostate-specific antigen outcomes after reimplant were examined. We described our reimplant planning and intraoperative procedure. In all 7 patients, we were able to achieve very favorable dosimetry after the second procedure. The acute toxicity of the reimplant procedure was re...Continue Reading

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Citations

Jul 21, 2011·Physics in Medicine and Biology·Junghoon LeeJerry L Prince
Aug 7, 2013·Radiation Oncology·Paul Martin PutoraDaniel Engeler
Mar 23, 2013·The British Journal of Radiology·L G Marcu, J M Lawson
Jul 3, 2009·International Journal of Radiation Oncology, Biology, Physics·Tom PicklesW James Morris
Nov 28, 2008·International Journal of Radiation Oncology, Biology, Physics·W James MorrisRyan Woods
May 24, 2008·International Journal of Radiation Oncology, Biology, Physics·Marco ZaiderAnatoly B Rosenfeld
Jul 21, 2010·IEEE Transactions on Medical Imaging·Junghoon LeeJerry L Prince
Oct 9, 2013·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Peter J HoskinGerry J Lowe

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