PMID: 6107678Nov 15, 1980Paper

13-cis retinoic acid and acne

Lancet
H JonesW J Cunliffe

Abstract

Patients with very severe acne which had not responded to conventional treatment were given 13-cis retinoic acid (0.1 mg-1.0 mg/kg body-weight) in a double-blind dose response study. Sebum excretion rate was reduced by 75% at 4 weeks, and all patients had an 80% improvement in their acne severity after 4 months treatment. There were dose-related side-effects, particularly dryness of the skin and mucous membranes. No patient wished to stop treatment.

References

Feb 15, 1979·The New England Journal of Medicine·G L PeckJ Arnaud-Battandier
Apr 5, 1969·Lancet·W J Cunliffe, S Shuster
Sep 1, 1969·The British Journal of Dermatology·W J Cunliffe, S Shuster
Aug 1, 1971·The British Journal of Dermatology·J L BurtonS Shuster
Mar 15, 1980·Lancet

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Citations

Jan 1, 1991·Archives of Dermatological Research·J L LévêqueG E Piérard
Jan 1, 1984·Archives of Dermatological Research·R HennesH J Vogt
Nov 30, 1984·Clinica Chimica Acta; International Journal of Clinical Chemistry·J R MarsdenS Shuster
Jan 1, 1989·Pharmacology & Therapeutics·S I White, R M MacKie
Sep 1, 1993·The British Journal of Dermatology·A M LaytonW J Cunliffe
Mar 1, 1992·International Journal of Dermatology·J HaglerM Sandbank
Jan 1, 1994·International Journal of Dermatology·M ShahidullahC L Goh
Feb 12, 1998·The Australasian Journal of Dermatology·A J Cooper
Mar 28, 1981·British Medical Journal·R Smith
Feb 1, 1982·The Journal of Clinical Investigation·D Douer, H P Koeffler
Apr 2, 2014·TheScientificWorldJournal·Amber VyasBina Gidwani
Sep 24, 2015·The Journal of Dermatological Treatment·Jennifer OrnelasRaja K Sivamani
May 20, 2003·The Australasian Journal of Dermatology·Alan J Cooper, UNKNOWN Australian Roaccutane Advisory Board
Jan 17, 2007·The British Journal of Dermatology·V MadanA M Marsland
Sep 5, 2012·Expert Review of Clinical Pharmacology·A H Schmitt-HoffmannP Kovacs
Apr 1, 2006·Current Medical Research and Opinion·Peter W Taylor, Michael H J Keenan
Jun 13, 2009·Expert Opinion on Drug Metabolism & Toxicology·Jayne E Thatcher, Nina Isoherranen
Mar 1, 1988·Clinical and Experimental Dermatology·J S PrendivilleR Russell-Jones
Nov 1, 1986·Clinical and Experimental Dermatology·J F Norris, W J Cunliffe
Mar 23, 2017·Immunology Letters·Peter A Tauber, Winfried F Pickl
Aug 14, 1998·Journal of the American Academy of Dermatology·J J Leyden
Mar 1, 1996·Journal of the American Academy of Dermatology·J M GeigerJ H Saurat
Dec 1, 1992·Journal of the American Academy of Dermatology·A M Layton, W J Cunliffe
Apr 1, 2006·The Journal of Investigative Dermatology·Amanda M NelsonDiane M Thiboutot
Apr 1, 1982·Journal of the American Academy of Dermatology·C H DickenL A Schachner
Apr 1, 1982·Journal of the American Academy of Dermatology·G L PeckJ Cheripko
Apr 1, 1982·Journal of the American Academy of Dermatology·J A GoldsteinJ S Strauss
Apr 1, 1982·Journal of the American Academy of Dermatology·G PlewigH H Wolff
Apr 1, 2010·The American Journal of Gastroenterology·Seth D CrockettMichael D Kappelman
Nov 1, 1982·The British Journal of Dermatology·F LyonsS Shuster
Mar 1, 1983·The British Journal of Dermatology·D H JonesW J Cunliffe
Jan 5, 2011·The Australasian Journal of Dermatology·Marius Rademaker
Sep 1, 1981·Clinical and Experimental Dermatology·W J CunliffeN B Simpson
Oct 12, 2001·Seminars in Cutaneous Medicine and Surgery·N Hanson, S Leachman
May 18, 2019·International Journal of Epidemiology·Catherine DroitcourtAlain Dupuy
Jun 21, 2019·Dalton Transactions : an International Journal of Inorganic Chemistry·Shirin KahremanyKrzysztof Palczewski
Aug 30, 2020·International Journal of Dermatology·Haady Fallah, Marius Rademaker
Nov 1, 1993·The Journal of Dermatology·D Hartmann, W Bollag
Oct 17, 2015·International Journal of Dermatology·Marius Rademaker
Aug 29, 2019·Organic & Biomolecular Chemistry·Shirin KahremanyKrzysztof Palczewski
Feb 20, 2009·Lasers in Surgery and Medicine·Hans-Joachim LaubachDieter Manstein
Oct 1, 1994·The Journal of Dermatology·D M Thappa, J Dogra

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