13-year-old girl with recurrent, episodic, persistent vomiting: out of the pot and into the fire

Pediatrics
Diana FeltonJenifer R Lightdale

Abstract

Cyclic vomiting syndrome (CVS) is a well-established cause of recurrent vomiting in the pediatric population. Severe vomiting with chronic cannabis use, known as cannabinoid hyperemesis syndrome, has recently been more widely recognized as an etiology of persistent episodic vomiting. In turn, patients presenting with frequent episodes of CVS are now increasingly being screened for cannabinoid use. Because patients with persistent vomiting are also frequently prescribed a proton pump inhibitor (PPI) for their gastrointestinal symptoms, it is important to be aware of the potential for a PPI to cause an interaction that can lead to false-positive urine cannabinoid screening. We describe a case of a false-positive urine cannabinoid screen in a patient with CVS who received a dose of intravenous pantoprazole. The primary reference regarding drug screen interference from PPIs can be found in the pantoprazole package insert that refers to pre-Food and Drug Administration approval data. Although multiple sources on the Internet report the possibility of positive cannabinoid screens from pantoprazole, there are no known published reports of the phenomenon in the medical literature.

References

Nov 1, 1995·Journal of Pediatric Gastroenterology and Nutrition·I Abu-Arafeh, G Russell
Sep 15, 1999·The Journal of Pediatrics·B U Li
Nov 29, 2007·The American Journal of Gastroenterology·Namita PareekThomas Abell
Jan 5, 2008·Mayo Clinic Proceedings·Karen E MoellerJulie C Kissack
Aug 30, 2008·Journal of Pediatric Gastroenterology and Nutrition·B U K LiUNKNOWN North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition
Sep 22, 2009·The Journal of Emergency Medicine·Michael W DonninoJonathan Fisher
May 21, 2010·Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie·Stephen Sullivan
Dec 14, 2011·Current Drug Abuse Reviews·Jonathan A GalliFrank K Friedenberg
May 29, 2012·European Journal of Gastroenterology & Hepatology·Lennard Y W LeeSimon Anderson
Jul 26, 2012·Clinical Chemistry·Vilte E BarakauskasGwendolyn A McMillin
Jul 31, 2013·The Journal of Emergency Medicine·Christopher Y Hopkins, Brandi L Gilchrist

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Citations

Oct 8, 2015·European Journal of Gastroenterology & Hepatology·James K RuffleAdam D Farmer
Mar 28, 2016·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·N Desjardins, C Stheneur
Dec 6, 2017·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Charles E ArgoffLynn R Webster
Nov 16, 2017·Medicine·Mostafa Ebraheem MorraKenji Hirayama
Nov 11, 2017·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Jennifer L PowersFrederick G Strathmann
Aug 3, 2018·Pediatrics in Review·George Sam Wang, Christopher Hoyte
Oct 10, 2018·Clinical Pediatrics·Rachel Silliman CohenAmy Goldberg
Jan 30, 2019·Current Opinion in Pediatrics·Eike BlohmMark Neavyn
Dec 31, 2019·F1000Research·Bhaskar Gurram, Ashish S Patel
Oct 1, 2019·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Varun VohraWilliam Eggleston
Dec 22, 2016·Journal of Medical Toxicology : Official Journal of the American College of Medical Toxicology·Cecilia J SorensenAndrew A Monte
Oct 7, 2017·Journal of Analytical Toxicology·Isabel GomilaMacarena Dastis
Feb 29, 2020·Pediatric Neurology·Gary N McAbeeYuri Brosgol
Nov 15, 2018·Medical Cannabis and Cannabinoids·Joseph V PergolizziJohn F Bisney

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