14-3-3 Proteins in Glutamatergic Synapses

Neural Plasticity
Jiajing Zhang, Yi Zhou

Abstract

The 14-3-3 proteins are a family of proteins that are highly expressed in the brain and particularly enriched at synapses. Evidence accumulated in the last two decades has implicated 14-3-3 proteins as an important regulator of synaptic transmission and plasticity. Here, we will review previous and more recent research that has helped us understand the roles of 14-3-3 proteins at glutamatergic synapses. A key challenge for the future is to delineate the 14-3-3-dependent molecular pathways involved in regulating synaptic functions.

References

Mar 1, 1995·Trends in Biochemical Sciences·A Aitken
Jun 3, 2000·Annual Review of Pharmacology and Toxicology·H FuS C Masters
Sep 29, 2001·The Journal of Biological Chemistry·S C Masters, H Fu
Oct 4, 2002·Current Biology : CB·Antje Gohla, Gary M Bokoch
Sep 3, 2003·Nature Reviews. Neuroscience·Daniela BergOlaf Riess
Jun 26, 2004·Annual Review of Neuroscience·Thomas C Sudhof
Nov 16, 2004·Nature Neuroscience·Fatma Simsek-DuranGyörgy Lonart
Apr 29, 2005·Cell Research·Paulette Mhawech
Jul 19, 2006·Cell and Tissue Research·Laurent Groc, Daniel Choquet
Sep 9, 2006·Molecular & Cellular Proteomics : MCP·Pierre-Olivier AngrandAmparo Acker-Palmer
May 22, 2007·Nature Reviews. Neuroscience·C Geoffrey Lau, R Suzanne Zukin
Sep 19, 2008·Proceedings of the National Academy of Sciences of the United States of America·Pascal S KaeserThomas C Südhof
Dec 25, 2009·Apoptosis : an International Journal on Programmed Cell Death·Weidong CaoZhou Fei
Feb 19, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Ying Yang, Nicole Calakos
Apr 8, 2010·Biological Chemistry·Tobias MittelstaedtSusanne Schoch
Mar 26, 2011·Proceedings of the National Academy of Sciences of the United States of America·Amy J RamseyMarc G Caron
Oct 11, 2011·Seminars in Cell & Developmental Biology·Jing ZhaoHaian Fu
Dec 26, 2012·Bioorganic & Medicinal Chemistry·Christian Ottmann
Apr 16, 2013·Neuropharmacology·Qiang Zhou, Morgan Sheng
Jul 19, 2013·The Journal of Biological Chemistry·Changcheng SunYong Li
Dec 11, 2013·Frontiers in Neural Circuits·Brent AsricanShengli Zhao
Apr 4, 2014·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Haifa QiaoYi Zhou
Sep 5, 2014·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Kazuhito Toyo-okaAnthony Wynshaw-Boris
May 8, 2015·Molecular Neurobiology·Matthias SchmitzInga Zerr

❮ Previous
Next ❯

Citations

Aug 10, 2019·Journal of Neuropathology and Experimental Neurology·Hannah C Kinney, Robin L Haynes
Oct 17, 2019·Frontiers in Cellular Neuroscience·Dominik R GabrychMichael A Silverman
Sep 12, 2020·Biomarker Insights·Elena CamporesiHenrik Zetterberg
Mar 30, 2021·Frontiers in Neural Circuits·Zachary B JonesYi Zhou
May 7, 2021·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·André S L M AntunesDaniel Martins-de-Souza
May 11, 2021·Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring·Johanna NilssonAnn Brinkmalm
Jul 3, 2021·International Journal of Molecular Sciences·Nicholas H HarbinJohn R Hepler
Jan 19, 2022·Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·A I FedinK R Badalyan

❮ Previous
Next ❯

Methods Mentioned

BETA
electrophoresis
transgenic
GTPase

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

International Journal of Biochemistry and Molecular Biology
Molly Foote, Yi Zhou
Current Biology : CB
A Shaw
Expert Opinion on Therapeutic Targets
Christopher L Neal, Dihua Yu
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
Haifa QiaoYi Zhou
© 2022 Meta ULC. All rights reserved