14-year-old boy with painful nail changes

Pediatrics in Review
Shudeshna NagSaul Greenberg

Abstract

Doxycycline is a classically implicated cause of phototoxic reactions. Photo-onycholysis is a rare manifestation of phototoxicity. Nail changes may typically include nail pain, subungual hemorrhages, or distal onycholysis. Self-resolution can be expected in 3 to 6 months. Patients prescribed doxycycline should be counseled about the potential for phototoxicity and the need for appropriate sun protection while taking the medication.

References

Dec 1, 1987·Journal of the American Academy of Dermatology·R Baran, L Juhlin
Jul 6, 2000·Pediatrics·C K YongA G Davidson
Jul 31, 2004·BMJ : British Medical Journal·Anneke PassierEugène van Puijenbroek
Dec 1, 2004·Journal of Travel Medicine·Didier RabarFrançois Peyron
Aug 11, 2007·Expert Opinion on Drug Safety·Kevin R Stein, Noah S Scheinfeld

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