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18 F-labeled benzimidazopyridine derivatives for PET imaging of tau pathology in Alzheimer's disease

Bioorganic & Medicinal Chemistry

Aug 15, 2019

Sho KaideMasahiro Ono

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Abstract

Hyperphosphorylated tau proteins are one of the neuropathological hallmarks in the Alzheimer's disease (AD) brain. The in vivo imaging of tau aggregates with nuclear medical imaging probes is helpful for the further comprehension of and medical intervention in the AD pathology. For tau-...read more

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Alzheimer's Disease
Amyloid
Analogs & derivatives
Brain
Brain Diseases
Diagnostic Imaging
Metabolism
Laboratory mice
Pathology
Drug Kinetics
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18 F-labeled benzimidazopyridine derivatives for PET imaging of tau pathology in Alzheimer's disease

Bioorganic & Medicinal Chemistry

Aug 15, 2019

Sho KaideMasahiro Ono

PMID: 31285098

DOI: 10.1016/j.bmc.2019.06.039

Abstract

Hyperphosphorylated tau proteins are one of the neuropathological hallmarks in the Alzheimer's disease (AD) brain. The in vivo imaging of tau aggregates with nuclear medical imaging probes is helpful for the further comprehension of and medical intervention in the AD pathology. For tau-...read more

Mentioned in this Paper

Alzheimer's Disease
Amyloid
Analogs & derivatives
Brain
Brain Diseases
1
2

Related Papers

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