18 F-sodium fluoride positron emission tomography of the racing Thoroughbred fetlock: Validation and comparison with other imaging modalities in nine horses

Equine Veterinary Journal
Mathieu SprietSusan M Stover

Abstract

Early and accurate detection of stress remodelling in racehorses is of utmost importance to prevent catastrophic injuries. Current imaging techniques have limitations in assessing early changes predisposing to catastrophic breakdowns. Positron emission tomography (PET) using 18 F-sodium fluoride (18 F-NaF) is a sensitive method for the detection of early bone turnover and may improve early recognition of subtle injuries. To validate the clinical use of 18 F-NaF PET in Thoroughbred racehorses, to assess the value of PET in the detection of bone lesions and to compare PET results with findings of other advanced imaging modalities, clinical examination and pathology. Experimental exploratory study. Twenty fetlocks from nine Thoroughbred racehorses were imaged using 18 F-NaF PET, computed tomography (CT) and scintigraphy. Five fetlocks were also imaged with magnetic resonance imaging and four fetlocks were also examined histologically. Imaging findings were independently reviewed by three board certified radiologists. Imaging, clinical and histopathological findings were correlated. PET imaging was well-tolerated by all horses. PET detected focal areas of 18 F-NaF uptake in instances where other imaging modalities did not identify ...Continue Reading

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Citations

Apr 6, 2019·Equine Veterinary Journal·M Spriet
Jun 12, 2020·Equine Veterinary Journal·Victoria A ColgateCelia M Marr
Aug 5, 2020·Equine Veterinary Journal·Sarah Plevin, Jonathan McLellan
Nov 20, 2020·Equine Veterinary Journal·Pieter H L Ramzan
Nov 17, 2020·Frontiers in Veterinary Science·Lea WalkerSteven Trostle
Jan 14, 2021·Equine Veterinary Journal·Allen E PageDavid W Horohov
Feb 17, 2021·PET Clinics·William Y RaynorMona-Elisabeth Revheim
Apr 16, 2021·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Ehren McLartyAmy S Kapatkin
May 28, 2021·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Monika A SamolSusan M Stover
May 31, 2021·Equine Veterinary Journal·Holly L StewartChristopher E Kawcak

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