18 F]FDG-PET/CT texture analysis in thyroid incidentalomas: preliminary results

European Journal of Hybrid Imaging
Martina SolliniMargarita Kirienko

Abstract

significance of incidental thyroid 2-deoxy-2-[18F]fluoro-D-glucose ([18F]FDG) uptake on positron emission tomography/computed tomography (PET/CT) scans remains controversial. We aimed to evaluate the ability of [18F]FDG-PET/CT texture analysis to predict final diagnosis in thyroid incidentaloma. We retrospectively evaluated medical records of all patients who performed a [18F]FDG-PET/CT from January 2012 to October 2016. Those patients who presented a thyroid incidentaloma described in the medical records and performed a fine needle aspiration in our institution were considered for the analysis. Cytological and/or histological results were used as reference standard to define the final diagnosis. In case of negative cytology, the nodule was considered benign. In case of non-diagnostic or inconclusive results ultrasound, follow-up and further cytology/histology were used as final diagnosis. For suspected or positive cytological result, histology was used as reference standard. PET images were segmented using a General Electric AW workstation running PET VCAR software (GE Healthcare, Waukesha, WI, USA) settled with a threshold of 40% SUVmax. LifeX software (http://www.lifexsoft.org) was used to perform texture analysis. Statistic...Continue Reading

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Citations

Jun 11, 2020·Thyroid : Official Journal of the American Thyroid Association·Luca CerianiLuca Giovanella
Oct 23, 2020·Nuclear Medicine and Molecular Imaging·Ayşegül AksuGamze Çapa Kaya
Mar 7, 2021·Diagnostics·Manuel Piñeiro-FielPablo Aguiar

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Methods Mentioned

BETA
features extraction

Software Mentioned

DICOM
SIAPEC
LifeX
PET VCAR

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