18F-DOPA Uptake of Developmental Venous Anomalies in Children With Brain Tumors

Clinical Nuclear Medicine
Giovanni MoranaAndrea Rossi

Abstract

We report the finding of increased F-3,4-dihydroxyphenylalanine uptake of the brain parenchyma adjacent to developmental venous anomalies, incidentally discovered in 3 pediatric patients with diffusely infiltrating gliomas. One patient presented 3 developmental venous anomalies located distant from the tumor, whereas in the remaining 2 patients, the vascular anomalies were inside the tumoral area mimicking a focal area of increased tumor metabolism. In the setting of brain tumor imaging, focal increased F-3,4-dihydroxyphenylalanine uptake should be carefully interpreted in light of MRI findings, and nuclear medicine physicians should be aware of any incidental minor vascular abnormality for proper interpretation of PET data.

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Citations

Dec 8, 2017·Clinical Nuclear Medicine·Lee Condon, John Blazak
Apr 29, 2019·European Journal of Nuclear Medicine and Molecular Imaging·Arnoldo PiccardoGiovanni Morana

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