18F-FDG PET for Detection of Primary Tracheobronchial T-/Natural Killer-Cell-Derived Posttransplant Lymphoproliferative Disorder After Lung Transplantation

Clinical Nuclear Medicine
Thorsten DerlinKatja Hueper

Abstract

Posttransplant lymphoproliferative disorder (PTLD) is a rare, but potentially devastating complication of solid organ transplantation. Epstein-Barr virus-associated PTLDs of T-cell origin are exceedingly rare. We present the case of a 20-year-old man with extranasal T-/natural killer-cell-derived PTLD after lung transplantation who underwent an F-FDG PET/CT scan for staging of disease. The F-FDG-PET scan demonstrated an unusual pattern of lymphomatous involvement limited to the recipients tracheobronchial tree without concomitant involvement of the donor's bronchi. This case highlights the potential of F-FDG PET/CT for sensitive detection and staging of uncommon manifestations of PTLD.

References

Feb 7, 2001·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·V LeblondV Levy
Aug 13, 2014·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Bruce D ChesonT Andrew Lister
Aug 19, 2015·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Gayathri KumarasingheJohn J Moore
May 18, 2016·Nature Reviews. Disease Primers·Vikas R DharnidharkaSylvain Choquet
May 20, 2017·Clinical Nuclear Medicine·Punit Sharma, Shilpa Bhartia

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Citations

Dec 28, 2018·Clinical Nuclear Medicine·Xu YangJigang Yang

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