18F-FDG PET/CT Prediction of an Aggressive Clinical Course for Dermatofibrosarcoma Protuberans

Journal of Nuclear Medicine Technology
Sandip Basu, Fahim Goliwale

Abstract

The ability to assess tumor biology is a benefit of molecular imaging with (18)F-FDG PET/CT, which performs better than anatomic imaging in evaluating malignancies. We present an unusual case of fatal dermatofibrosarcoma protuberans, a usually indolent entity for which high-grade (18)F-FDG uptake was predictive of an aggressive clinical course unabated by tyrosine kinase inhibitor imatinib mesylate, to which the patient showed a poor response.

References

Aug 31, 2002·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Brian P RubinJames D Bruckner
Oct 27, 2004·Cancer·William M MendenhallMark T Scarborough
Oct 20, 2009·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Hossein JadvarSanjiv S Gambhir
Jan 13, 2011·European Journal of Nuclear Medicine and Molecular Imaging·Thomas C KweeAbass Alavi
Jun 2, 2015·Expert Review of Anticancer Therapy·Piotr Rutkowski, Maria Debiec-Rychter

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Citations

Aug 2, 2018·Contrast Media & Molecular Imaging·Dao-Ning LiuChun-Yi Hao
Aug 11, 2017·Current Treatment Options in Oncology·Alvaro E Acosta, Catalina Santa Vélez

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