2-aryl-3-(1H-azol-1-yl)-1H-indole derivatives: a new class of antimycobacterial compounds - conventional heating in comparison with MW-assisted synthesis

Archiv der Pharmazie
Daniele ZampieriLuciano Vio

Abstract

2-Aryl-3-(1H-imidazol-1-yl and 1H-1,2,4-triazol-1-yl)-1H-indole derivatives were synthesized and tested for their in-vitro antifungal and antimycobacterial activities. These indole derivatives were devoid of antifungal activity against the tested strains of Candida spp. Yet, they exhibited an interesting antitubercular activity against Mycobacterium tuberculosis reference strain H(37)Rv.

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Citations

Mar 24, 2011·Future Medicinal Chemistry·Prem M S ChauhanMoni Sharma
Aug 16, 2012·Molecular Diversity·Gökçe Cihan-Üstündağ, Gültaze Capan
Apr 25, 2015·Journal of Enzyme Inhibition and Medicinal Chemistry·Gökçe Cihan-ÜstündağGültaze Çapan

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