2-octylcyanoacrylate-assisted microvascular anastomosis: comparison with a conventional suture technique in rat femoral arteries

Journal of Reconstructive Microsurgery
E S AngI C Song

Abstract

Standard microvascular anastomosis using only sutures is a well-established and successful technique; however, it is time-consuming and may cause vessel narrowing, needle trauma, and tissue reaction. The authors' hypothesis was that 2-octylcyanoacrylate could simplify microvascular anastomosis and reduce wall trauma and reaction. End-to-end anastomoses of the femoral arteries were performed in 20 adult rats. Each animal served as its own control. The time taken for each anastomosis (from first stitch to release of clamps) was noted, and the patency assessed. At day 7, the anastomoses were reassessed for patency, and the vessels evaluated histologically. 2-octylcyanoacrylate reduced the need to insert more sutures. Anastomotic time in the study group was statistically significantly shorter (p < 0.001), and the patency rate was 90 percent, compared to 85 percent with the standard suture technique. There was also less intense inflammatory reaction, with fewer foreign-body granulomata. This is the first report on the use of 2-octylcyanocrylate, currently approved for cutaneous use, for vessel anastomosis. Further work on the biomechanics and long-term histologic effects will be carried out. 2-octylcyanoacrylate has the potential fo...Continue Reading

Citations

Apr 1, 2010·Langenbeck's Archives of Surgery·Wei WeiJieshou Li
Feb 11, 2004·American Journal of Surgery·Adam J Singer, Henry C Thode
May 23, 2002·The Annals of Thoracic Surgery·Marc P BuijsroggeCornelius Borst
Jan 1, 2010·Journal of Surgical Technique and Case Report·G M BotE D Dung
Apr 25, 2007·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Balázs B LorinczImre Gerlinger
Oct 30, 2012·Hand Clinics·Raymond Tse, Jason H Ko
May 4, 2010·International Journal of Oral and Maxillofacial Surgery·T LandegrenA Sondén
Jul 1, 2008·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·M Gürhan UlusoyDerya Oztuna
Apr 11, 2015·Surgery Today·Yoshiyuki SaitoMasaki Kitajima
Dec 13, 2006·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Byung-Ho ChoiJingxu Li
Nov 24, 2004·International Journal of Oral and Maxillofacial Surgery·B-H ChoiB-P Cho
Apr 6, 2004·Facial Plastic Surgery Clinics of North America·Tessa Hadlock, Mark Varvares
Feb 13, 2003·The Journal of Thoracic and Cardiovascular Surgery·Marc P BuijsroggeCornelius Borst
Mar 26, 2003·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·A TiwariA M Seifalian
Aug 1, 1991·Journal of Vascular Surgery·P F LawrenceG R Goodman
Nov 30, 2004·Thrombosis Research·Brian C CooleyYvonne Datta
Feb 21, 2003·The British Journal of Surgery·C J ZeebregtsR van Schilfgaarde
May 12, 2011·The Journal of Craniofacial Surgery·Onur EgemenLutfu Bas
Jun 27, 2006·Annals of Plastic Surgery·Ibrahim OrakLevent Yildiz
Jul 22, 2018·The Journal of Craniofacial Surgery·Xiangdang LiangZhanshe Guo
Jul 22, 2005·Annals of Plastic Surgery·Angela Piñeros-FernándezGeorge T Rodeheaver
Apr 21, 2007·European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes·D SabaM Cengiz
Mar 12, 2020·Interactive Cardiovascular and Thoracic Surgery·Desiree WusslerNora Lang
Sep 22, 2007·Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery·Thomas LandegrenJonas K E Persson
Jun 6, 2020·Annals of Plastic Surgery·Nathan ChowBrendan MacKay

❮ Previous
Next ❯

Related Concepts

Related Feeds

Biomechanics

Biomechanics examines the generation of internal forces within the body and investigates the effects and control of forces that act on or are produced on tissues. Here are the latest discoveries.