2017/18 and 2018/19 seasonal influenza vaccine safety surveillance, Canadian National Vaccine Safety (CANVAS) Network

Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin
Julie A BettingerCanadian Immunization Research Network

Abstract

BackgroundThe Canadian National Vaccine Safety (CANVAS) network monitors the safety of seasonal influenza vaccines in Canada.AimTo provide enhanced surveillance for seasonal influenza and pandemic influenza vaccines.MethodsIn 2017/18 and 2018/19 influenza seasons, adults (≥ 15 years of age) and parents of children vaccinated with the seasonal influenza vaccine participated in an observational study using web-based active surveillance. Participants completed an online survey for health events occurring in the first 7 days after vaccination. Participants who received the influenza vaccine in the previous season, but had not yet been vaccinated for the current season, were unvaccinated controls.ResultsIn 2017/18, 43,751 participants and in 2018/19, 47,798 completed the online safety survey. In total, 957 of 30,173 participants vaccinated in 2017/18 (3.2%; 95% confidence interval (CI): 3.0-3.4) and 857 of 25,799 participants vaccinated in 2018/19 (3.3%; 95% CI: 3.1-3.5) reported a health problem of sufficient intensity to prevent their normal daily activities and/or cause them to seek medical care (including hospitalisation). This compared to 323 of 13,578 (2.4%; 95% CI: 2.1-2.6) and 544 of 21,999 (2.5%; 95% CI: 2.3-2.7) controls i...Continue Reading

References

Aug 13, 2003·Seminars in Pediatric Infectious Diseases·David W ScheifeleUNKNOWN CPS/Health Canada, Immunization Monitoring Program, Active (IMPACT)
Jun 17, 2009·Journal of Occupational and Environmental Medicine·Meghan E ShortMark G Wilson
Jul 18, 2012·PloS One·Gaston De SerresUNKNOWN PHAC-CIHR influenza Research Network (PCIRN)
Nov 2, 2014·The Pediatric Infectious Disease Journal·Julie A BettingerJames D Kellner
Dec 9, 2014·Human Vaccines & Immunotherapeutics·Hazel J ClothierJim P Buttery
Aug 1, 2015·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·J A BettingerUNKNOWN Public Health Agency of Canada/Canadian Institutes for Health Research Influenza Research Network
Nov 6, 2015·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·Alexis PillsburyUNKNOWN AusVaxSafety, surveillance team
Nov 13, 2017·Vaccine·Alexis PillsburyUNKNOWN AusVaxSafety consortium

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