PMID: 5256995Mar 1, 1969Paper

23Na nuclear magnetic resonance relaxation studies of sodium ion interaction with soluble RNA

Proceedings of the National Academy of Sciences of the United States of America
T L James, J H Noggle

Abstract

Interactions between (23)Na(+) and soluble RNA in aqueous solution are studied with the use of (23)Na nuclear magnetic resonance. At low concentrations of NaCl, the interactions obey a simple equilibrium model with a formation constant log (K(f))(3) = 2.8 +/- 0.3. The relaxation rate of the bound sodium is found to be T(1B) (-1) = 222 +/- 19 sec(-1) compared to that of free sodium T(1F) (-1) = 17.5 sec(-1). At high NaCl concentrations, the system deviates from the model, possibly owing to aggregation of the soluble RNA.

References

Feb 1, 1967·Biochimica Et Biophysica Acta·C A RotunnoM Cereijido
May 1, 1966·Proceedings of the National Academy of Sciences of the United States of America·T R Stengle, J D Baldeschwieler
Mar 22, 1968·Science·I C SmithR G Shulman
Jun 7, 1967·Journal of the American Chemical Society·T R Stengle, J D Baldeschwieler
Sep 7, 1967·Biochemical and Biophysical Research Communications·R L Ward, J A Happe

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Citations

Feb 1, 1992·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·L S PrinceG A Elgavish
Dec 1, 1987·Journal of Bioenergetics and Biomembranes·B Cornell
Apr 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·D W UrryM A Khaled
Jun 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·M L BleamM T Record
Mar 11, 1981·Nucleic Acids Research·D R BurtonP Reimarsson
Mar 30, 1973·Annals of the New York Academy of Sciences·H J Berendsen, H T Edzes
Jan 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·J ReubenE J Gabbay
Apr 15, 1970·Biochimica Et Biophysica Acta·A Rupprecht, B Forslind
Apr 24, 1970·Biochemical and Biophysical Research Communications·J A MagnusonN S Magnuson
Sep 16, 1980·Biochemical and Biophysical Research Communications·D W UrryS Oparil
Sep 10, 1970·Biochemical and Biophysical Research Communications·R G Bryant
May 1, 1973·Biochemical and Biophysical Research Communications·J Andrasko, S Forsén
May 12, 2004·Journal of Inorganic Biochemistry·Chandra SrinivasanDuarte Mota de Freitas
Feb 1, 1978·FEBS Letters·H GustavssonL A Fransson
Dec 31, 2004·Magnetic Resonance in Chemistry : MRC·Allan M TorresPhilip W Kuchel
Sep 1, 1990·Scandinavian Journal of Clinical and Laboratory Investigation·H NissenM Hørder
Aug 27, 1999·Archives of Biochemistry and Biophysics·W LinK W Olsen
Nov 1, 1993·Journal of Inorganic Biochemistry·J A CowanL Y Hsu

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