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2,4-Dinitrophenol blocks neurodegeneration and preserves sciatic nerve function after trauma

Journal of Neurotrauma

Feb 11, 2010

Rodrigo F Madeiro da CostaSérgio T Ferreira

Abstract

Preventing the harm caused by nerve degeneration is a major challenge in neurodegenerative diseases and in various forms of trauma to the nervous system. The aim of the current work was to investigate the effects of systemic administration of 2,4-dinitrophenol (DNP), a compound with new...read more

Mentioned in this Paper

Nervousness
Abnormal Degeneration
Heart Block
Structure of Sciatic Nerve
Immunoreactivity
Immunologic Adjuvants
Sciatic Neuritis
2,4-Dinitrophenol
Adjuvant
Entire Nervous System
1
21
Paper Details
References
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  • Citations10
1234
  • References39
  • Citations10
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2,4-Dinitrophenol blocks neurodegeneration and preserves sciatic nerve function after trauma

Journal of Neurotrauma

Feb 11, 2010

Rodrigo F Madeiro da CostaSérgio T Ferreira

PMID: 20143955

DOI: 10.1089/neu.2009.1189

Abstract

Preventing the harm caused by nerve degeneration is a major challenge in neurodegenerative diseases and in various forms of trauma to the nervous system. The aim of the current work was to investigate the effects of systemic administration of 2,4-dinitrophenol (DNP), a compound with new...read more

Mentioned in this Paper

Nervousness
Abnormal Degeneration
Heart Block
Structure of Sciatic Nerve
Immunoreactivity
Immunologic Adjuvants
Sciatic Neuritis
2,4-Dinitrophenol
Adjuvant
Entire Nervous System
1
21

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GDF15 in Appetite & Homeostasis

Growth differentiation factor 15 (GDF15) is a stress response cytokine that directly acts on the feeding centres in the brain and plays a role in regulation of energy homeostasis. Here is the latest research on mechanisms underlying GDF15 function in appetite and homeostasis.

GFRAL/GDF15 Signaling

GFRAL is a receptor for growth differentiation factor 15 (GDF15). These proteins play a role in regulating inflammatory pathways, as well as cell repair, apoptosis, and cell growth. Here is the latest research on GFRAL/GDF15-mediated signal transduction.

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Paper Details
References
  • References39
  • Citations10
1234
  • References39
  • Citations10
1
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