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2,4-toluenediisocyanate and hexamethylene-diisocyanate adducts with blood proteins: assessment of reactivity of amino acid residues in vitro

Chemico-biological Interactions

Jan 29, 1999

J P Mráz, S Bousková

PMID: 10190575

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Abstract

Diisocyanates, reactive compounds used in plastics industry and potent occupational allergens, readily bind to proteins both in vitro and in vivo, however, the pattern of adducts with individual amino acids has not been investigated systematically. In this study, potential of the protei...read more

Mentioned in this Paper

Cysteine
Amino Acid [EPC]
Blood Proteins
Acetylcysteine
1,6-hexamethylene diisocyanate
ALB gene
Globin Activity
Amines
Cyclohexane
Albumins
7
Paper Details
References
  • References9
  • Citations8
1

2,4-toluenediisocyanate and hexamethylene-diisocyanate adducts with blood proteins: assessment of reactivity of amino acid residues in vitro

Chemico-biological Interactions

Jan 29, 1999

J P Mráz, S Bousková

PMID: 10190575

DOI:

Abstract

Diisocyanates, reactive compounds used in plastics industry and potent occupational allergens, readily bind to proteins both in vitro and in vivo, however, the pattern of adducts with individual amino acids has not been investigated systematically. In this study, potential of the protei...read more

Mentioned in this Paper

Cysteine
Amino Acid [EPC]
Blood Proteins
Acetylcysteine
1,6-hexamethylene diisocyanate
7

Related Papers

Paper Details
References
  • References9
  • Citations8
1

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