3-dimensional neuroanatomy of the human fetal pelvis: anatomical support for partial urogenital mobilization in the treatment of urogenital sinus

The Journal of Urology
Nicolas KalfaLaurence S Baskin

Abstract

Retrospective reviews suggest that the functional outcomes of surgery of the urogenital sinus have often been unsatisfactory and to our knowledge the long-term results of newer surgical techniques have yet to be evaluated. A precise understanding of pelvic fetal neuroanatomy is germane for optimizing surgical correction of the urogenital sinus. The pelves of 10 human female fetuses were serially sectioned. Masson's trichrome staining and immunochemistry for the neuronal marker S100 (Dako Corp., Carpinteria, California) along with anatomical computer reconstruction allowed 3-dimensional analysis of the nerves in relation to the pelvic structures as an animated motion picture. Two types of neuronal structures were identified. 1) A dense perivisceral foil of branching nerves closely surrounded the pelvic organs. The localization of most nerves was on the external faces of the viscera with a limited fraction in the rectovaginal and urethrovaginal septa. This innervation was from the anterior cephalad periurethral area to the posterior caudal perirectal area. 2) A significant amount of nerves surrounded the cephalad urethra on its anterior and posterior faces. Based on these anatomical data during surgical repair of a urogenital sin...Continue Reading

References

Jun 1, 1992·Journal of Pediatric Surgery·A PeñaC Stolar
Apr 1, 1990·The Journal of Urology·R Gonzalez, E T Fernandes
Feb 1, 1997·Journal of Pediatric Surgery·A Peña
Jul 17, 1998·World Journal of Urology·R C Rink, M C Adams
Jun 15, 1999·BJU International·B LudwikowskiR González
Aug 24, 1999·The Journal of Urology·L S BaskinG R Cunha
Nov 1, 2000·Pediatric Surgery International·S CelayirN Danişmend
May 24, 2001·The Journal of Urology·A FarkasI Hadas-Halpren
Jul 4, 2001·The Journal of Urology·Y AkmanL S Baskin
Sep 6, 2002·The Journal of Clinical Endocrinology and Metabolism·UNKNOWN Joint LWPES/ESPE CAH Working Group.
Jun 18, 2004·The Journal of Urology·Selcuk YucelLaurence S Baskin
Nov 13, 2004·The Journal of Urology·John V Kryger, Ricardo González
May 17, 2005·BJU International·Melissa C DaviesSarah M Creighton
Apr 13, 2007·BJU International·Naomi S Crouch, Sarah M Creighton
Oct 25, 2008·Journal of Pediatric Urology·R C RinkM P Cain

❮ Previous
Next ❯

Citations

Jan 13, 2011·Surgical and Radiologic Anatomy : SRA·David MoszkowiczFrédérique Peschaud
Jul 24, 2012·The Journal of Urology·Christopher R J WoodhouseSarah Creighton
Nov 22, 2011·Journal of Pediatric Urology·Riitta FagerholmSeppo Taskinen
Sep 22, 2009·The Journal of Urology·Futoshi MatsuiAkio Kubota
May 3, 2016·Journal of Pediatric Urology·Pierre D E MouriquandPeter Lee
Jul 19, 2014·The Journal of Urology·Allen D Seftel
Oct 3, 2018·The Journal of Clinical Endocrinology and Metabolism·Phyllis W SpeiserPerrin C White
Sep 3, 2009·Current Opinion in Obstetrics & Gynecology

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.